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Impact of disease risk on efficacy of matched related bone marrow transplantation for pediatric acute myeloid leukemia: the Children's Oncology Group.
Author: , AlonzoTodd A, BectonDavid, GerbingRobert B, HoranJohn T, LangeBeverly J, LymanGary H, RavindranathYaddanapudi, SmithFranklin O, WoodsWilliam G
Original Abstract of the Article :
There is considerable variation in the use of HLA-matched related bone marrow transplantation (BMT) for the treatment of pediatric patients with newly diagnosed acute myeloid leukemia (AML). Some oncologists have argued that BMT should be offered to most patients in first complete remission (CR). Ot...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645105/
データ提供:米国国立医学図書館(NLM)
Matched Related Bone Marrow Transplantation: A Valuable Tool for Pediatric Acute Myeloid Leukemia
Pediatric acute myeloid leukemia (AML) is a serious and often life-threatening cancer. This study, published in [Journal Name], investigates the efficacy of HLA-matched related bone marrow transplantation (BMT) in treating pediatric patients with newly diagnosed AML. The researchers analyzed data from a large cohort study (Children's Oncology Group) to determine the impact of disease risk on the effectiveness of BMT.
BMT: A Potentially Life-Saving Treatment for High-Risk AML
The study found that BMT was associated with improved outcomes for pediatric patients with high-risk AML. The researchers concluded that BMT should be considered as a treatment option for these patients, potentially offering a chance for long-term remission and survival.
Personalizing Treatment: Balancing Risks and Benefits
The study highlights the importance of carefully weighing the risks and benefits of BMT for each individual patient. The authors suggest that BMT may be particularly beneficial for patients with high-risk AML, who may have a higher likelihood of relapse if treated with chemotherapy alone.
Dr.Camel's Conclusion
Like a camel navigating the harsh desert of cancer treatment, this study provides valuable insights into the potential benefits of BMT for pediatric patients with high-risk AML. The researchers have highlighted the importance of personalized treatment approaches, considering both the risks and benefits of BMT for each individual patient. The findings offer hope for those facing this challenging diagnosis, providing evidence-based support for the use of BMT as a potentially life-saving treatment option.
Date :
- Date Completed 2009-01-06
- Date Revised 2018-11-13
Further Info :
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