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Distinct vascular and metabolic effects of different classes of anti-hypertensive drugs.
Author: HanSeung Hwan, KimSoo Jin, KohKwang Kon, KohYesl, LeeYonghee, QuonMichael J, ShinEak Kyun
Original Abstract of the Article :
ASCOT-BPLA study demonstrates that in hypertensive subjects, atenolol+bendroflumethiazide therapy is associated with higher incidence of adverse cardiovascular outcomes and developing diabetes than an amlodipine+perindopril regimen. This is not explained by changes in blood pressure alone. We hypoth...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/19059660
データ提供:米国国立医学図書館(NLM)
Antihypertensive Drugs: A Journey Through Different Landscapes of Cardiovascular Health
Hypertension, like a slow-burning desert fire, can silently damage the cardiovascular system. While various antihypertensive drugs are available, their effects beyond blood pressure reduction remain a topic of ongoing investigation. This study, like a caravan exploring different routes across the desert, investigated the distinct vascular and metabolic effects of different classes of antihypertensive drugs.
Unveiling the Unique Effects of Antihypertensive Drugs
The study, analyzing data from the ASCOT-BPLA trial, found that atenolol+bendroflumethiazide therapy was associated with a higher incidence of adverse cardiovascular outcomes and diabetes development compared to amlodipine+perindopril. These findings, like a series of footprints in the sand, indicate that the choice of antihypertensive drugs may have significant implications for overall cardiovascular health.
Navigating the Choices in Antihypertensive Therapy
This study underscores the importance of considering the individual needs and risk factors of patients when choosing an antihypertensive drug. The study's findings highlight the need for further research into the long-term effects of different drug classes, potentially leading to more personalized and effective treatment strategies.
Dr.Camel's Conclusion
This research reminds us that the desert of hypertension is complex and diverse. The choice of antihypertensive drugs, like selecting the best path through this desert, is crucial for achieving optimal cardiovascular health. Understanding the unique effects of different drug classes is essential for tailoring treatment plans to meet individual needs and minimize the risk of adverse outcomes.
Date :
- Date Completed 2010-06-21
- Date Revised 2021-12-03
Further Info :
Related Literature
English
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