Distinct vascular and metabolic effects of different classes of anti-hypertensive drugs.

Author: HanSeung Hwan, KimSoo Jin, KohKwang Kon, KohYesl, LeeYonghee, QuonMichael J, ShinEak Kyun

Paper Details 
Original Abstract of the Article :
ASCOT-BPLA study demonstrates that in hypertensive subjects, atenolol+bendroflumethiazide therapy is associated with higher incidence of adverse cardiovascular outcomes and developing diabetes than an amlodipine+perindopril regimen. This is not explained by changes in blood pressure alone. We hypoth...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/19059660

データ提供:米国国立医学図書館(NLM)

Antihypertensive Drugs: A Journey Through Different Landscapes of Cardiovascular Health

Hypertension, like a slow-burning desert fire, can silently damage the cardiovascular system. While various antihypertensive drugs are available, their effects beyond blood pressure reduction remain a topic of ongoing investigation. This study, like a caravan exploring different routes across the desert, investigated the distinct vascular and metabolic effects of different classes of antihypertensive drugs.

Unveiling the Unique Effects of Antihypertensive Drugs

The study, analyzing data from the ASCOT-BPLA trial, found that atenolol+bendroflumethiazide therapy was associated with a higher incidence of adverse cardiovascular outcomes and diabetes development compared to amlodipine+perindopril. These findings, like a series of footprints in the sand, indicate that the choice of antihypertensive drugs may have significant implications for overall cardiovascular health.

Navigating the Choices in Antihypertensive Therapy

This study underscores the importance of considering the individual needs and risk factors of patients when choosing an antihypertensive drug. The study's findings highlight the need for further research into the long-term effects of different drug classes, potentially leading to more personalized and effective treatment strategies.

Dr.Camel's Conclusion

This research reminds us that the desert of hypertension is complex and diverse. The choice of antihypertensive drugs, like selecting the best path through this desert, is crucial for achieving optimal cardiovascular health. Understanding the unique effects of different drug classes is essential for tailoring treatment plans to meet individual needs and minimize the risk of adverse outcomes.

Date :
  1. Date Completed 2010-06-21
  2. Date Revised 2021-12-03
Further Info :

Pubmed ID

19059660

DOI: Digital Object Identifier

NIHMS192307

SNS
PICO Info
in preparation
Languages

English

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