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The relative toxicity of nonsteroidal antiinflammatory drugs.

Author: BlochD A, FriesJ F, WilliamsC A

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

Nonsteroidal anti-inflammatory drugs (NSAIDs) varied significantly in toxicity, with indomethacin, tolmetin sodium, and meclofenamate sodium being the most toxic.
Paper Details　
Original Abstract of the Article :
Toxicity Index scores were computed from symptoms, laboratory abnormalities, and hospitalizations attributed to nonsteroidal antiinflammatory drug (NSAID) therapy in 2,747 patients with rheumatoid arthritis receiving 5,642 courses of 11 NSAIDs over 8,481 patient-years. Substantial differences in ove...See full text at original site
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引用元：
https://doi.org/10.1002/art.1780341103

データ提供：米国国立医学図書館（NLM）

Nonsteroidal Anti-inflammatory Drugs (NSAIDs): A Desert of Side Effects

This research delves into the potential side effects of nonsteroidal anti-inflammatory drugs (NSAIDs), a common class of medications used for pain relief. The study, analyzing data from a large cohort of patients with rheumatoid arthritis, aimed to assess the relative toxicity of different NSAIDs. The authors found significant differences in toxicity levels among various NSAIDs, with some drugs exhibiting higher rates of adverse effects compared to others. This analysis provides important information for healthcare professionals and patients in making informed decisions about NSAID use.

Navigating NSAIDs: A Careful Approach

This study highlights the importance of considering potential side effects when using NSAIDs. The findings suggest that some NSAIDs carry a higher risk of adverse effects than others. It's crucial to discuss your medical history and potential risks with your healthcare provider to determine the most appropriate NSAID for your individual needs. This research serves as a reminder to approach NSAID use with careful consideration.

NSAIDs: A Balancing Act

Just as a camel must carefully navigate a desert landscape, using NSAIDs requires a balanced approach. This research underscores the importance of understanding the potential risks and benefits of different NSAIDs. It's essential to work closely with your healthcare provider to make informed decisions about your medication choices. This research provides valuable insights into the potential complexities of NSAID use, emphasizing the need for careful consideration and personalized treatment.

Dr. Camel's Conclusion

This research provides valuable insights into the potential side effects of NSAIDs, emphasizing the need for careful consideration and personalized treatment. Just as a camel navigates a vast and unpredictable desert, using NSAIDs requires a thoughtful approach, taking into account individual needs and potential risks. Working closely with your healthcare provider is essential for making informed decisions about medication choices and ensuring a safe and effective treatment journey.

Date :
  1. Date Completed 1991-11-25
  2. Date Revised 2019-07-17
Further Info :

Pubmed ID

1953813

DOI: Digital Object Identifier

10.1002/art.1780341103

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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