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Switching from oral cholinesterase inhibitors to the rivastigmine transdermal patch.
Author: BouchardR W, GoodmanI, PerezJ A Davila, SadowskyC, TekinS
Original Abstract of the Article :
Oral cholinesterase inhibitors (ChEIs) are associated with side effects such as nausea and vomiting. The use of transdermal patches for ChEI delivery may help to minimize these problems. The objective of this review was to consider available data from patients switching from oral ChEIs to transderma...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6493826/
データ提供:米国国立医学図書館(NLM)
Switching Gears: From Oral Cholinesterase Inhibitors to Rivastigmine Patches
This research investigates the practicality and safety of switching patients from oral cholinesterase inhibitors (ChEIs), medications used to treat Alzheimer's disease, to the rivastigmine transdermal patch. The authors recognize that oral ChEIs often cause unpleasant side effects like nausea and vomiting. They reviewed clinical trial data and observational studies to assess the feasibility and safety of switching patients to the rivastigmine patch. Their findings suggest that this switch can be well-tolerated, with low rates of nausea and vomiting reported in patients switching from various oral ChEI medications. They also provide specific recommendations for switching regimens based on patients' previous oral ChEI dosage.
Improving Patient Comfort and Adherence
The research suggests that switching patients from oral ChEIs to the rivastigmine patch could significantly improve their quality of life by reducing bothersome side effects. It also highlights the importance of individualized treatment approaches, tailoring the switch based on a patient's specific needs and medication history. The insights gleaned from this research could help patients with Alzheimer's disease better manage their condition and potentially improve their overall well-being.
Practical Implications for Patients
For patients with Alzheimer's disease who are currently taking oral ChEIs and experiencing side effects, this study provides hope for a more comfortable and effective treatment option. It's important to discuss the potential benefits and risks of switching to the rivastigmine patch with a healthcare professional. This research also underscores the importance of patient education, empowering individuals with Alzheimer's disease to actively participate in their treatment decisions.
Dr. Camel's Conclusion
Think of switching from oral ChEIs to the rivastigmine patch as a camel caravan transitioning from a bumpy desert path to a smoother, more comfortable route. This study helps us navigate the complex world of medication management, finding ways to improve patient comfort and make the journey smoother for those battling Alzheimer's disease.
Date :
- Date Completed 2010-03-23
- Date Revised 2021-10-20
Further Info :
Related Literature
English
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