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[Cutaneous side effects of the multikinase inhibitors sorafenib and sunitinib].

Author: EamesT, StaehlerM, WollenbergA

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Molecular targeted therapy with monoclonal antibodies and low molecular weight inhibitors is gaining importance in the treatment of malignant tumors. The multikinase inhibitors sorafenib and sunitinib have a favorable tolerability profile but can induce specific cutaneous side effects, which can be indicators of antitumor activity.
Paper Details　
Original Abstract of the Article :
Molecular targeted therapy with monoclonal antibodies and low molecular weight inhibitors is gaining increasing importance particularly in the treatment of malignant tumors. These drugs are specific and highly selective agents that intervene in the dysfunctional regulatory processes of malignant cel...See full text at original site
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難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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引用元：
https://doi.org/10.1007/s00105-010-1942-7

データ提供：米国国立医学図書館（NLM）

Unveiling the Skin's Secrets: Exploring Cutaneous Side Effects of Multikinase Inhibitors

The landscape of cancer treatment is evolving rapidly, with targeted therapies becoming increasingly prevalent. This study focuses on the cutaneous side effects of two multikinase inhibitors, sorafenib and sunitinib, which target specific molecular pathways in cancer cells. It offers a detailed comparison of the side effects associated with these drugs, providing valuable insights for clinicians and patients alike.

Skin as a Window to Cancer Treatment

The research emphasizes the significance of cutaneous side effects as potential indicators of antitumor activity. These side effects, while often manageable, provide a window into the effectiveness of the treatment and can guide adjustments in therapy.

Navigating the Skin's Response to Targeted Therapies

This study underscores the importance of understanding the potential cutaneous side effects of targeted therapies. By recognizing these side effects and knowing how to manage them, patients can better navigate the challenges of cancer treatment and improve their quality of life.

Dr.Camel's Conclusion

Just like a camel's tough hide protects it from the harsh desert sun, our skin can offer clues about the effectiveness of cancer treatments. This research reminds us that even seemingly minor side effects can be vital signals in the fight against this disease.

Date :
  1. Date Completed 2011-01-04
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

20631979

DOI: Digital Object Identifier

10.1007/s00105-010-1942-7

SNS
PICO Info
in preparation
Languages

German

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