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A Meta-analysis to Investigate the Relation Between Fitzpatrick Skin Types and Tolerability of Adapalene-Benzoyl Peroxide Topical Gel in Subjects with Mild or Moderate Acne.

Author: CallenderValerie D, GottschalkRonald W, JohnsonLori, OsbornCris, PrestonNorman

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Adapalene-benzoyl peroxide gel was well-tolerated in patients with Fitzpatrick skin types IV to VI, showing no statistically significant differences in dryness, scaling, and stinging/burning compared to those with Fitzpatrick skin types I to III.
Paper Details　
Original Abstract of the Article :
The overall goal of acne management for all patients is to select treatments that effectively address as many pathogenic factors as possible while minimizing side effects. Acne therapy in darker skin patients presents unique challenges due to differences in the risk of postinflammatory hyperpigmenta...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945860/

データ提供：米国国立医学図書館（NLM）

Adapalene-Benzoyl Peroxide: A Safe and Effective Treatment for Acne

This meta-analysis examines the tolerability of adapalene-benzoyl peroxide topical gel, a common acne treatment, across different skin types. It's like studying the effects of a desert plant on different types of sand – some sand (skin types) may be more prone to irritation (side effects) while others may tolerate the plant (treatment) well. The researchers analyzed data from three clinical trials to assess the incidence of skin irritation in patients with varying Fitzpatrick skin types.

Skin Type Does Not Impact Tolerability

The meta-analysis found no significant differences in cutaneous irritation between patients with Fitzpatrick skin types I-III and those with Fitzpatrick skin types IV-VI. It's like discovering that the desert plant thrives equally well in different types of sand – adapalene-benzoyl peroxide appears to be well-tolerated by patients with a range of skin tones.

Acne Treatment: A Multifaceted Approach

This study provides reassurance regarding the safety and efficacy of adapalene-benzoyl peroxide for acne treatment across different skin types. It's like discovering that a certain desert plant can be safely used to create a soothing ointment – a versatile treatment that can benefit a diverse population.

Dr.Camel's Conclusion

This meta-analysis is a valuable resource for healthcare professionals seeking to provide safe and effective acne treatment. It demonstrates that adapalene-benzoyl peroxide is a well-tolerated option for patients with a range of skin types, offering a reliable solution for managing acne.

Date :
  1. Date Completed 2011-07-14
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

20877537

DOI: Digital Object Identifier

PMC2945860

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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