Methylphenidate for treating tobacco dependence in non-attention deficit hyperactivity disorder smokers: a pilot randomized placebo-controlled trial.

Author: CroghanIvana T, EbbertJon O, HaysJ Taylor, HurtRichard D, SchroederDarrell R, SoodAmit

Paper Details 
Original Abstract of the Article :
Methylphenidate blocks the re-uptake of dopamine by binding to the dopamine transporter in the presynaptic cell membrane and increases extracellular dopamine levels. Similarities in neuropsychologic effects between nicotine and methylphenidate make it an intriguing potential therapeutic option. Prev...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038986/

データ提供:米国国立医学図書館(NLM)

Methylphenidate: A Potential Ally in the Fight Against Tobacco Dependence?

This research delves into the potential of methylphenidate, a medication commonly used to treat attention-deficit/hyperactivity disorder (ADHD), as a treatment for tobacco dependence. The authors conducted a pilot randomized placebo-controlled trial to investigate the effects of methylphenidate on smoking cessation in non-ADHD smokers. This research is like exploring a new oasis in the desert of smoking cessation, seeking to uncover a potential source of relief for smokers.

Methylphenidate: A Promising New Path for Smoking Cessation?

While the pilot study provided preliminary evidence suggesting a potential benefit of methylphenidate in reducing nicotine withdrawal symptoms, it did not demonstrate significant efficacy in helping smokers quit. This research underscores the need for further investigation and larger-scale studies to fully evaluate the potential of methylphenidate as a smoking cessation aid. This is like encountering a promising oasis in the desert, but requiring further exploration to determine its true value and sustainability.

Navigating the Desert of Smoking Cessation

This research highlights the ongoing search for effective treatments for tobacco dependence. While methylphenidate showed some potential in the pilot study, further research is needed to validate its efficacy and establish its place in the armamentarium of smoking cessation therapies. This is like navigating a vast desert, constantly seeking new oases and pathways to guide smokers towards a smoke-free future.

Dr. Camel's Conclusion

This pilot study offers an intriguing peek into the potential of methylphenidate for treating tobacco dependence. While the findings are promising, more research is needed to determine its true efficacy and safety. It's like discovering a hidden oasis in the desert, a potential source of hope, but requiring further exploration and validation to ensure its long-term sustainability and benefits for smokers.

Date :
  1. Date Completed 2011-06-16
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

21276244

DOI: Digital Object Identifier

PMC3038986

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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