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The effect of adding psychodynamic therapy to antidepressants in patients with major depressive disorder. A systematic review of randomized clinical trials with meta-analyses and trial sequential analyses.

Author: GluudChristian, HansenJane Lindschou, JakobsenJanus Christian, SimonsenErik

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Adding psychodynamic therapy to antidepressants might benefit depressed patients, but the possible treatment effect measured on the Hamilton Rating Scale for Depression is small. Psychodynamic therapy significantly reduced depressive symptoms on the 17-item Hamilton Rating Scale for Depression (mean difference -3.01 (95% confidence interval -3.98 to -2.03; P<0.00001), no significant heterogeneity between trials) compared with 'no intervention'.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Major depressive disorder afflicts an estimated 17% of individuals during their lifetimes at tremendous suffering and costs. Psychodynamic therapy may be a treatment option for depression, but the effects have only been limitedly assessed in systematic reviews. METHOD: Using Cochrane sy...See full text at original site
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引用元：
https://doi.org/10.1016/j.jad.2011.03.035

データ提供：米国国立医学図書館（NLM）

The Role of Psychodynamic Therapy in Depression

This study examines the effectiveness of psychodynamic therapy in conjunction with antidepressant medication for individuals with major depressive disorder. The researchers conducted a systematic review and meta-analysis of randomized clinical trials, rigorously evaluating the benefits and harms of psychodynamic therapy compared to no intervention or sham treatment.

Psychodynamic Therapy: A Potential Adjunct to Antidepressants

The meta-analysis revealed that adding psychodynamic therapy to antidepressant medication significantly reduced depressive symptoms compared to antidepressants alone. However, the study noted that the effect size was small, suggesting that the benefits may be modest.

Understanding the Diverse Approaches to Mental Health

This research highlights the importance of exploring various therapeutic approaches for mental health conditions. Psychodynamic therapy, with its focus on uncovering underlying emotional patterns, may offer a valuable complement to traditional antidepressant medication.

Dr.Camel's Conclusion

As diverse and unpredictable as the desert landscape can be, so too are the experiences of mental health. This study suggests that psychodynamic therapy, like a gentle breeze across the dunes, may offer a soothing and restorative effect for individuals with depression. However, as with all therapies, personalized approaches are key to achieving optimal outcomes.
Date :
  1. Date Completed 2012-04-27
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

21501877

DOI: Digital Object Identifier

10.1016/j.jad.2011.03.035

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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