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Pharmacological effects of methylphenidate on plasma homovanillic acid and growth hormone.
Author: DavisJ M, EastonM, JavaidJ I, PandeyG N, SharmaR P
Original Abstract of the Article :
The acute pharmacological actions of methylphenidate, a potent psychotogenic stimulant, were studied by measuring plasma homovanillic acid (HVA) and serum growth hormone (GH) as indices of presynaptic and postsynaptic functions, respectively. Twenty psychiatric inpatients participated in a double-bl...See full text at original site
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引用元:
https://doi.org/10.1016/0165-1781(90)90130-w
データ提供:米国国立医学図書館(NLM)
Exploring Methylphenidate's Effects: A Double-Blind Study
Methylphenidate is a medication commonly used to treat attention-deficit/hyperactivity disorder (ADHD). This research investigates the pharmacological effects of methylphenidate on plasma homovanillic acid (HVA) and serum growth hormone (GH) levels. The study employed a double-blind, placebo-randomized design, administering methylphenidate or placebo to psychiatric inpatients. The authors found that methylphenidate significantly increased GH levels, particularly in male participants, but had no immediate impact on HVA levels. However, a decrease in HVA was observed 24 hours after methylphenidate administration, suggesting a possible long-term effect on dopamine neurotransmission.
Unveiling Methylphenidate's Actions: Insights into Neurotransmission
The study provides valuable insights into the neurobiological mechanisms of methylphenidate. Just as a camel adapts to the desert environment by regulating its water intake, methylphenidate's impact on GH and HVA levels suggests its influence on different neurochemical pathways. The study's findings contribute to our understanding of how this medication interacts with the brain.
Managing ADHD: Understanding Medications and Their Effects
Individuals with ADHD should consult with a healthcare professional to discuss the best treatment options, including medication, therapy, and lifestyle modifications. It's important to understand the potential side effects of medications and to work closely with your doctor to monitor your progress and adjust treatment as needed. Remember, seeking professional guidance and collaborating with your healthcare team can empower you to manage ADHD effectively.
Dr.Camel's Conclusion
This research adds to our understanding of how methylphenidate impacts the brain. Just as a camel uses its unique adaptations to navigate the desert, this medication works on specific neurochemical pathways to address the symptoms of ADHD. By understanding the effects of medication and working with healthcare professionals, individuals with ADHD can find effective strategies for managing their condition and achieving a better quality of life.
Date :
- Date Completed 1990-07-12
- Date Revised 2019-08-24
Further Info :
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