Influence of comorbidities and age on risk of death without recurrence: a retrospective analysis of the Arimidex, Tamoxifen Alone or in Combination trial.

Author: BaumMichael, BuzdarAman, CuzickJack, DowsettMitch, ForbesJohn F, HowellAnthony, RingAlistair, SestakIvana

Paper Details 
Original Abstract of the Article :
The Arimidex, Tamoxifen Alone or in Combination (ATAC) study was a double-blind randomized trial in which postmenopausal women with early-stage breast cancer were assigned to receive anastrozole, tamoxifen, or the combination. We have conducted a retrospective analysis to examine the effects of como...See full text at original site
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引用元:
https://doi.org/10.1200/JCO.2011.35.5545

データ提供:米国国立医学図書館(NLM)

The Impact of Comorbidities and Age on Breast Cancer Outcomes

The field of oncology is constantly striving to improve outcomes for patients diagnosed with breast cancer. This research delves into the influence of comorbidities and age on the treatment received and subsequent outcomes in women with early-stage breast cancer. The authors conducted a retrospective analysis of the ATAC study, a randomized trial comparing anastrozole, tamoxifen, and a combination of the two treatments. Their findings highlight the importance of considering individual patient characteristics, including comorbidities and age, when making treatment decisions and predicting outcomes.

Comorbidities and Age: Crucial Factors in Breast Cancer Treatment

The authors' analysis underscores the importance of considering individual patient characteristics when making treatment decisions for breast cancer. Their findings suggest that age and the presence of comorbidities can significantly impact the treatment received and the likelihood of both breast cancer-related and non-breast cancer-related mortality. This research emphasizes the need for personalized medicine approaches, taking into account the unique characteristics of each patient to tailor treatment plans for optimal outcomes.

Navigating the Complexities of Breast Cancer Treatment: A Personalized Approach

Breast cancer is a complex disease, and treatment decisions must be made carefully, considering the individual patient's circumstances. This research provides valuable insights into the influence of age and comorbidities on breast cancer outcomes, highlighting the importance of individualized treatment approaches. By understanding these factors, clinicians can develop treatment plans that are more likely to lead to optimal outcomes for their patients.

Dr.Camel's Conclusion

Just like a camel navigating a diverse desert landscape, the journey through breast cancer treatment requires a personalized approach. This research illuminates the impact of age and comorbidities on treatment choices and outcomes, emphasizing the importance of tailoring treatment plans to meet the unique needs of each patient. The quest for better breast cancer treatments continues, and recognizing the individuality of each patient is a crucial step in achieving optimal outcomes.

Date :
  1. Date Completed 2011-12-22
  2. Date Revised 2022-01-29
Further Info :

Pubmed ID

21990403

DOI: Digital Object Identifier

10.1200/JCO.2011.35.5545

SNS
PICO Info
in preparation
Languages

English

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