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Linagliptin monotherapy in type 2 diabetes patients for whom metformin is inappropriate: an 18-week randomized, double-blind, placebo-controlled phase III trial with a 34-week active-controlled extension.
Author: BarnettA H, HarperR, PatelS, ThiemannS, ToorawaR, WoerleH-J, von EynattenM
Original Abstract of the Article :
AIMS: To investigate the efficacy and safety of linagliptin, a dipeptidyl peptidase-4 inhibitor, in type 2 diabetes mellitus (T2DM) patients for whom metformin was inappropriate. METHODS: This 1-year double-blind study (ClinicalTrials.gov, NCT00740051) enrolled T2DM patients with inadequate glycaem...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1111/dom.12011
データ提供:米国国立医学図書館(NLM)
Linagliptin: A New Hope for Type 2 Diabetes Management?
This study delves into the world of type 2 diabetes and explores the efficacy and safety of linagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, as a monotherapy for patients ineligible for metformin. The research provides insights into linagliptin's potential as an alternative treatment option for managing blood sugar levels in individuals with type 2 diabetes.
Linagliptin: A Promising Option for Type 2 Diabetes
The study found that linagliptin significantly improved glycaemic control in type 2 diabetes patients who were unable to take metformin, leading to a reduction in HbA1c levels compared to placebo. Moreover, linagliptin demonstrated better tolerability compared to glimepiride, with fewer episodes of hypoglycemia and weight gain.
Managing Type 2 Diabetes: Understanding Treatment Options
These findings contribute to the growing body of knowledge about DPP-4 inhibitors and their potential role in type 2 diabetes management. It's important to consult with a healthcare professional to determine the most appropriate treatment plan, considering individual needs and risk factors. Understanding the benefits and risks of different treatment options is key to making informed decisions about managing type 2 diabetes.
Dr.Camel's Conclusion
Type 2 diabetes, like a desert mirage, can play tricks on our bodies. Linagliptin, like a cool desert breeze, might help regulate blood sugar levels and make managing this condition easier. But remember, like a mirage, it's essential to seek professional guidance to navigate the complex world of diabetes treatment.
Date :
- Date Completed 2015-02-23
- Date Revised 2017-02-03
Further Info :
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