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Effects of extended release methylphenidate treatment on ratings of attention-deficit/hyperactivity disorder (ADHD) and associated behavior in children with autism spectrum disorders and ADHD symptoms.

Author: AmanMichael G, ArnoldL Eugene, BuksteinOscar G, CasatCharles D, ClevelandLynne A, FactorPerry, JergerSusan W, LaneDavid M, LovelandKatherine A, MansourRosleen, PearsonDeborah A, PerezEvelyn, SantosCynthia W, VanwoerdenSalome

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.

Overview

MPH formulations are efficacious and well-tolerated for children with ASD and significant ADHD symptoms.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: The purpose of this study was to examine the behavioral effects of four doses of psychostimulant medication, combining extended-release methylphenidate (MPH) in the morning with immediate-release MPH in the afternoon. METHOD: The sample comprised 24 children (19 boys; 5 girls) who met Am...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689935/

データ提供：米国国立医学図書館（NLM）

Effects of Methylphenidate on Children with Autism Spectrum Disorders

This research explores a vital area in the field of [child neurology]. The study delves into the effects of [methylphenidate (MPH) medication] on children diagnosed with [Autism Spectrum Disorders (ASD)] who also exhibit symptoms of [Attention-Deficit/Hyperactivity Disorder (ADHD)]. Using a [within-subject, crossover, placebo-controlled design], researchers administered [four different doses of MPH] to [24 children] and observed the impact on their behavior, both at home and school.

Promising Results for Children with ASD and ADHD

The study's findings are truly exciting! The researchers observed that [MPH treatment was associated with significant declines in hyperactive and impulsive behavior]. Additionally, parents reported notable improvements in [inattentive and oppositional behavior] as well as [social skills] in their children. It's important to note that [no exacerbation of stereotypies was noted, and side effects were similar to those seen in typically developing children with ADHD]. These results indicate that [MPH formulations are efficacious and well-tolerated for children with ASD and significant ADHD symptoms].

Hopeful Insights for Parents and Children

This research brings hope to families dealing with the challenges of [ASD and ADHD]. It suggests that [medication may be a viable option for managing the behavioral difficulties associated with these conditions]. However, it's crucial to consult with a qualified physician and discuss the potential benefits and risks of [MPH] treatment.

Dr. Camel's Conclusion

This research is a beacon of hope in the vast desert of challenges faced by children with ASD and ADHD. It sheds light on the potential of [MPH] as a therapeutic tool to improve their lives. However, as with any treatment, it's crucial to consider individual needs and consult with medical professionals to determine the best course of action. The research reminds us that even in the face of seemingly insurmountable challenges, we can find solutions that bring comfort and hope to those in need.

Date :
  1. Date Completed 2014-02-10
  2. Date Revised 2022-03-30
Further Info :

Pubmed ID

23782128

DOI: Digital Object Identifier

PMC3689935

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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