Biological vs. conventional combination treatment and work loss in early rheumatoid arthritis: a randomized trial.

Author: BrattJohan, ErikssonJonas K, ErnestamSofia, GeborekPierre, NeoviusMartin, PeterssonIngemar F, van VollenhovenRonald F

Paper Details 
Original Abstract of the Article :
The introduction of biological tumor necrosis factor inhibitors has improved the treatment of rheumatoid arthritis (RA) but at a substantial cost. These drugs have been shown to lead to superior radiological outcomes compared with a combination of conventional disease-modifying antirheumatic drugs o...See full text at original site
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引用元:
https://doi.org/10.1001/jamainternmed.2013.7801

データ提供:米国国立医学図書館(NLM)

Biological vs. Conventional Treatment for Early Rheumatoid Arthritis

The field of [rheumatology] continues to make strides in treating [rheumatoid arthritis], an autoimmune disease causing [joint inflammation and pain]. This research compares two common treatment approaches: [biological tumor necrosis factor inhibitors] and [conventional disease-modifying antirheumatic drugs]. The researchers conducted a [randomized controlled trial], a gold standard for evaluating treatment effectiveness, to compare the impact of these therapies on [work loss] in individuals with [early rheumatoid arthritis]. This research is like a desert expedition, where two different paths lead to a destination, but each path presents its own unique challenges and advantages.

Biological Therapies Show Promise: A Trade-Off Between Efficacy and Cost

The results of this research provide valuable insights for individuals with [early rheumatoid arthritis]. The researchers found that [biological tumor necrosis factor inhibitors] led to [superior radiological outcomes] compared to [conventional disease-modifying antirheumatic drugs] over a [two-year period]. However, the researchers also acknowledge the [high cost] associated with [biological therapies]. It's like choosing between two paths in the desert: one is shorter and more direct but requires a toll, while the other is longer but free. This research emphasizes the need for careful consideration of [treatment costs and benefits] when choosing the best course of action for [rheumatoid arthritis].

Making Informed Decisions About Rheumatoid Arthritis Treatment

Individuals with [early rheumatoid arthritis] should consult with their [rheumatologist] to discuss the [benefits and drawbacks] of different treatment options. This research underscores the importance of [personalized treatment plans] that consider factors such as [disease severity, individual preferences, and financial constraints]. It's like choosing the right supplies for a desert journey - different supplies are needed for different terrains and objectives. This research contributes to the growing body of knowledge on [rheumatoid arthritis treatment] and helps individuals make informed decisions about their health and well-being.

Dr.Camel's Conclusion

This research, like a desert explorer's map, helps us navigate the complex world of rheumatoid arthritis treatment. While biological therapies may offer superior outcomes, their high cost necessitates careful consideration. Understanding the pros and cons of different options empowers individuals to make informed decisions about their health journey.

Date :
  1. Date Completed 2013-12-10
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

23817631

DOI: Digital Object Identifier

10.1001/jamainternmed.2013.7801

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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