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Maintenance treatment with varenicline for smoking cessation in patients with schizophrenia and bipolar disorder: a randomized clinical trial.

Author: AchtyesEric D, AyerDavid, CatherCorinne, EvinsA Eden, GoffDonald C, HoeppnerSusanne S, PachasGladys N, PrattSarah A, SchoenfeldDavid A

Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study found that among smokers with serious mental illness who attained initial abstinence with standard treatment, maintenance pharmacotherapy with varenicline and cognitive behavioral therapy improved prolonged tobacco abstinence rates compared with cognitive behavioral therapy alone after 1 year of treatment and at 6 months after treatment discontinuation.
Paper Details　
Original Abstract of the Article :
IMPORTANCE: It is estimated that more than half of those with serious mental illness smoke tobacco regularly. Standard courses of pharmacotherapeutic cessation aids improve short-term abstinence, but most who attain abstinence relapse rapidly after discontinuation of pharmacotherapy. OBJECTIVE: To ...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/24399553

データ提供：米国国立医学図書館（NLM）

Maintenance Varenicline for Smoking Cessation in Mental Illness

In the field of [psychiatry], researchers are constantly working to find effective treatments for complex conditions. This study explored the potential of maintenance pharmacotherapy with varenicline, a medication commonly used for smoking cessation, in individuals with schizophrenia and bipolar disorder. The study, utilizing a [randomized, double-blind, placebo-controlled design], found that maintenance varenicline, combined with cognitive behavioral therapy, significantly increased the rate of prolonged tobacco abstinence compared to cognitive behavioral therapy alone.

Varenicline Shows Promise for Smoking Cessation in Mental Illness

The study revealed that maintenance varenicline treatment significantly increased the likelihood of long-term abstinence from smoking among individuals with schizophrenia and bipolar disorder. These findings suggest that varenicline could be a valuable tool for helping patients with mental illness overcome nicotine addiction.

Mental Health and Addiction: A Complex Relationship

This research highlights the complexities of treating addiction in individuals with mental illness. It underscores the need for multifaceted approaches that address both the psychological and physiological aspects of addiction. Just as a camel needs to navigate challenging terrain and adapt to harsh conditions, individuals with mental illness may need specialized care and tailored therapies to address their unique challenges.

Dr.Camel's Conclusion

This study shines a light on the promising role of pharmacotherapy in managing addiction within the context of mental illness. It demonstrates the potential for varenicline to provide lasting support for individuals seeking to break free from the grip of nicotine addiction. It reminds us that the pursuit of well-being is a collaborative journey between medical professionals and patients, and that understanding the individual’s unique needs is key to success.

Date :
  1. Date Completed 2014-01-13
  2. Date Revised 2022-03-17
Further Info :

Pubmed ID

24399553

DOI: Digital Object Identifier

NIHMS606183

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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