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Impact of medical treatments for male lower urinary tract symptoms due to benign prostatic hyperplasia on ejaculatory function: a systematic review and meta-analysis.

Author: CariniMarco, CoronaGiovanni, FicarraVincenzo, GacciMauro, MaggiMario, NovaraGiacomo, SebastianelliArcangelo, SerniSergio, ShariatShahrokh F, ZattoniFiliberto

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Alpha-blockers and 5ARIs are associated with a higher risk of ejaculatory dysfunction (EjD) than placebo. Combination therapy with both drug classes results in a 3-fold increased risk of EjD.
Paper Details　
Original Abstract of the Article :
INTRODUCTION: Several drugs, currently used to treat lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH), can be associated with bothersome sexual side effects, including ejaculatory dysfunction (EjD). AIM: To provide a systematic review and meta-analysis of the available ...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/24708055

データ提供：米国国立医学図書館（NLM）

Navigating the Desert of Benign Prostatic Hyperplasia (BPH)

Benign prostatic hyperplasia (BPH) is a common condition that affects men, often leading to lower urinary tract symptoms (LUTS). This study explores the impact of medical treatments for BPH on ejaculatory function, a sensitive issue for many men.

The authors conducted a systematic review and meta-analysis of randomized clinical trials investigating the effects of alpha-blockers, 5-alpha reductase inhibitors (5ARIs), and combination therapy on ejaculatory dysfunction (EjD). The results revealed that both alpha-blockers and 5ARIs were associated with a significantly higher risk of EjD compared to placebo. Furthermore, combination therapy led to a greater risk of EjD compared to either treatment alone.

A Desert Oasis of Knowledge

This meta-analysis provides a valuable roadmap for understanding the potential side effects of BPH medications on ejaculatory function. The findings suggest that specific alpha-blockers, such as Tamsulosin and Silodosin, may carry a higher risk of EjD than others. It is also noteworthy that the effectiveness of a given medication was correlated with the likelihood of EjD, highlighting the need for careful consideration of potential side effects alongside treatment efficacy.

A Camel's Compass for BPH Treatment

This research emphasizes the importance of open communication between patients and healthcare professionals regarding the potential side effects of BPH medications. While medications can provide relief from LUTS, it is crucial to weigh the benefits against the potential impact on sexual function.

Dr. Camel's Conclusion

This research, a journey through the desert of BPH treatment, emphasizes the need for a nuanced understanding of the potential side effects of medications. By weighing the benefits and risks, patients and healthcare providers can make informed decisions that prioritize both physical health and quality of life.

Date :
  1. Date Completed 2014-09-29
  2. Date Revised 2022-03-10
Further Info :

Pubmed ID

24708055

DOI: Digital Object Identifier

S1743-6095(15)30799-2

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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