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Management of osteoporosis with calcitriol in elderly Chinese patients: a systematic review.

Author: JiangYan, LiaoRuo-xi, XiaWeibo, YuMiao

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Calcitriol, an active vitamin D metabolite, is recommended for managing osteoporosis in China. This review summarizes six randomized controlled trials on calcitriol monotherapy and five trials on combined therapy. The findings suggest that calcitriol monotherapy can improve bone mineral density but may be insufficient for long-term treatment. Combined therapy with other bone agents is well-tolerated and demonstrates additional bone-preserving effects.
Paper Details　
Original Abstract of the Article :
Osteoporosis, a skeletal disorder characterized by a reduction in bone strength, is becoming a major public health problem in the People's Republic of China, with a rapid increase observed among the population. Chinese guidelines particularly recommend use of active vitamin D in managing osteoporosi...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974693/

データ提供：米国国立医学図書館（NLM）

Calcitriol: A Promising Oasis in the Desert of Osteoporosis

Osteoporosis, a condition characterized by weakened bones, can be a challenging and often debilitating experience, like traversing a brittle desert landscape. This systematic review explores the use of calcitriol, an active vitamin D metabolite, in managing osteoporosis, particularly in elderly Chinese patients.

The researchers analyzed data from multiple randomized controlled trials, evaluating the efficacy of calcitriol monotherapy and calcitriol in combination with other antiosteoporotic agents. They found that calcitriol, both alone and in combination, can improve bone mineral density, decrease bone turnover markers, and enhance muscle strength, suggesting its potential as a valuable tool in managing osteoporosis.

Navigating the Desert of Bone Health

This research provides valuable insights into the role of calcitriol in managing osteoporosis, particularly in elderly Chinese patients. It highlights the potential benefits of calcitriol in improving bone mineral density, reducing bone turnover markers, and enhancing muscle strength. This research serves as a guide for clinicians seeking effective treatment options for their patients with osteoporosis.

Finding Strength in the Desert of Bone Loss

This research offers a glimmer of hope for individuals struggling with osteoporosis. The effectiveness of calcitriol in improving bone health, reducing bone turnover markers, and enhancing muscle strength provides a promising treatment option. This research encourages individuals to discuss their treatment options with their healthcare provider, ensuring they receive the most appropriate and effective care to maintain bone health and prevent fractures.

Dr.Camel's Conclusion

This research sheds light on the potential of calcitriol in combating osteoporosis, particularly in elderly Chinese patients. It highlights the importance of personalized care and tailored treatment plans, ensuring that individuals receive the most appropriate interventions to preserve bone health and maintain mobility. This research underscores the ongoing efforts of researchers to develop effective treatments for osteoporosis, offering hope and support for those navigating the challenges of this debilitating condition.

Date :
  1. Date Completed 2014-12-15
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

24729692

DOI: Digital Object Identifier

PMC3974693

SNS
PICO Info
in preparation
Languages

English

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