Paper Details
- Home
- Paper Details
The effect of perindopril on blood pressure in humans on different sodium intakes.
Author: AndersonA, MorganT, MurphyJ, NowsonC, WilsonD
Original Abstract of the Article :
Perindopril is a new inhibitor of converting enzyme activity with a prolonged half-life. Thirty-two patients with essential hypertension and a diastolic blood pressure greater than 95 mm Hg were stratified into two groups according to their 24 h urine sodium excretion. They were randomized in a doub...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1097/00005344-198706107-00023
データ提供:米国国立医学図書館(NLM)
Perindopril and Blood Pressure: A Desert Oasis for High Blood Pressure?
The world of hypertension research is a vast and arid desert, filled with many challenges. One of the most important quests in this field is to discover new and effective medications that can help people manage their blood pressure effectively. This study delves into the effects of perindopril, a promising drug in the fight against hypertension. The research team employed a randomized double-blind study design, a crucial tool in the quest for scientific truth, to investigate the impact of perindopril on blood pressure in patients with essential hypertension. The researchers carefully observed the effects of perindopril on blood pressure across different sodium intake levels, a factor that can significantly influence blood pressure regulation.
Perindopril Shows Promise in the Desert of High Blood Pressure
The study revealed that perindopril effectively lowered blood pressure in both high and low sodium intake groups. This is a significant finding, suggesting that perindopril could be a valuable tool for managing blood pressure regardless of dietary habits, a bit like finding a refreshing oasis in the desert! The researchers found that perindopril reduced blood pressure by 22/11 mm Hg in a supine position and by 27/14 mm Hg in an erect position, compared to a negligible change in the placebo group. This suggests that perindopril's effects are consistently felt, regardless of body position, like a steady breeze across a desert landscape.
Maintaining Balance in the Desert: Perindopril and Sodium
The study's findings provide a glimmer of hope for individuals struggling with high blood pressure. It's encouraging to know that a drug like perindopril can work effectively across different sodium intake levels, allowing individuals to maintain some flexibility in their diet. However, as a cautious researcher, I always advocate for a holistic approach to health. While perindopril shows promise, it's crucial to work with your doctor to create a comprehensive plan that includes dietary adjustments, exercise, and stress management techniques. Remember, just like a desert traveler needs to be mindful of their water intake, maintaining a balanced lifestyle is crucial for overall health.
Dr. Camel's Conclusion
Perindopril is a promising antihypertensive drug that may offer a valuable solution for managing blood pressure regardless of sodium intake levels. While it shows potential in the fight against hypertension, remember to consult with your doctor to create a personalized plan that addresses your individual needs and lifestyle.
Date :
- Date Completed 1991-10-01
- Date Revised 2019-07-24
Further Info :
Related Literature
English
This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.