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Albuterol treatment for children with asthma: a comparison of inhaled powder and aerosol.

Author: BronskyE A, FurukawaC T, GrossmanJ, KempJ P, LemanskeR F, MansfieldL E, MurphyS, RatnerP H, ReeseM E, RogenesP R

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Albuterol, an asthma medication, was studied in children aged 4 to 12 years, comparing its efficacy and safety when administered as an aerosol or dry powder. Both formulations were equally effective in providing bronchodilation with minimal adverse effects. A majority of children preferred the powder delivery system.
Paper Details　
Original Abstract of the Article :
A dose-ranging study and a 12-week treatment study were conducted in children with asthma, aged 4 to 12 years, to assess the efficacy and safety of albuterol inhaled as either an aerosol or as dry powder. Both studies were double-blind and placebo-controlled with randomized assignment to treatment. ...See full text at original site
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引用元：
https://doi.org/10.1016/0091-6749(89)90085-7

データ提供：米国国立医学図書館（NLM）

Albuterol for Asthma: A Comparison of Delivery Methods

As a doctor specializing in respiratory health, I’m always looking for the best ways to help my patients manage their asthma. This research, conducted in children with asthma, compares the effectiveness of two different albuterol delivery methods – inhaled powder and aerosol. Albuterol is a common bronchodilator, helping to open up the airways and ease breathing. The researchers designed a double-blind, placebo-controlled study, carefully comparing the effects of both delivery methods. They recruited children aged 4 to 12 years, creating a diverse group of participants. This is akin to a desert exploration, where each child represents a different aspect of the terrain. The researchers conducted both dose-ranging and long-term treatment studies, carefully assessing the efficacy and safety of both delivery methods.

Delivery Methods: Equal Effectiveness

The findings of this research indicate that both inhaled powder and aerosol albuterol are equally effective in managing asthma symptoms in children. This is like finding two different paths through the desert – both leading to the same destination. Furthermore, both formulations were well-tolerated, with only minimal side effects. Interestingly, a significant number of children preferred the powder delivery method. This finding provides valuable information for clinicians and parents when choosing the best albuterol delivery method for their child.

Managing Asthma: Choosing the Right Approach

The research highlights the importance of individualized care when managing asthma. The findings suggest that both inhaled powder and aerosol albuterol are viable treatment options, and the preference of the child should be considered when making the choice. This is like choosing the best camel for a long desert journey – taking into account the needs and preferences of the traveler.

Dr.Camel’s Conclusion

This research provides valuable insights into the effectiveness and safety of different albuterol delivery methods in children with asthma. Like a seasoned guide leading a caravan through the desert, the researchers have navigated the complexities of asthma treatment, offering valuable information to clinicians and families.
Date :
  1. Date Completed 1989-05-03
  2. Date Revised 2019-07-23
Further Info :

Pubmed ID

2647819

DOI: Digital Object Identifier

10.1016/0091-6749(89)90085-7

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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