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Effects of perindopril on ambulatory intra-arterial blood pressure, cardiovascular reflexes and forearm blood flow in essential hypertension.

Author: LittlerW A, SmithS A, StallardT J, WestJ N

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.

Overview

Perindopril, an ACE inhibitor, was studied for its effects on ambulatory blood pressure, forearm blood flow, and cardiovascular reflexes in hypertensive patients. Perindopril significantly reduced blood pressure and increased forearm blood flow. It also augmented the bradycardia during facial immersion, suggesting an increase in parasympathetic tone.
Paper Details　
Original Abstract of the Article :
The effects of monotherapy with the angiotensin converting enzyme (ACE) inhibitor perindopril (8 mg once daily) on 24-h ambulatory intra-arterial blood pressure, forearm blood flow, left ventricular mass, vasoactive hormones and cardiovascular reflexes were determined in eight hypertensive patients ...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/2647846

データ提供：米国国立医学図書館（NLM）

Controlling Blood Pressure: A Journey Through the Desert of Hypertension

Hypertension, or high blood pressure, is a prevalent condition, like a desert where the air pressure is relentless and can impact overall well-being. This research explores the effects of perindopril, an angiotensin converting enzyme (ACE) inhibitor, on blood pressure and cardiovascular function, seeking a more effective way to manage this desert of hypertension.

Navigating the Desert of Hypertension With Perindopril

The researchers conducted a randomized double-blind, placebo-controlled cross-over study to evaluate the impact of perindopril on ambulatory blood pressure, forearm blood flow, and cardiovascular reflexes. The results demonstrated that perindopril effectively reduced blood pressure and increased forearm blood flow, akin to finding a cool oasis in a harsh desert landscape.

Living a Healthier Life in the Desert of Hypertension

These findings highlight the effectiveness of perindopril in managing hypertension, providing a potential solution to the challenges of this condition. It is crucial to consult with a healthcare professional to determine the most appropriate treatment strategy for individual needs and to monitor blood pressure regularly to ensure its effective management.

Dr.Camel's Conclusion

This research showcases the potential of perindopril in managing hypertension. It's like discovering a new, well-paved path through the desert of hypertension, making the journey more manageable and comfortable. The key is to remain vigilant and proactive, seeking out the best solutions to ensure a healthier future.

Date :
  1. Date Completed 1989-05-03
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

2647846

DOI: Digital Object Identifier

2647846

SNS
PICO Info
in preparation
Languages

English

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