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Natural course and response to interferon of chronic hepatitis B accompanied by antibody to hepatitis B e antigen.

Author: BoninoF, BrunettoM R, CapalboM, ChiabergeE, CriscuoloD, DavidE, OliveriF, RoccaG, VermeG

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

A study of 30 patients with chronic hepatitis B found that interferon alpha-2a treatment resulted in a rapid decrease in detectable hepatitis B virus DNA levels and normalized aminotransferase levels in eight patients. However, in seven patients, viral levels rebounded after treatment ended.
Paper Details　
Original Abstract of the Article :
The course of chronic hepatitis B was studied in 30 patients who had antibody to hepatitis e antigen and hepatitis B virus DNA in the serum and hepatitis B core antigen in the liver. Over a 2-year period, no patient experienced a sustained spontaneous remission of disease, and follow-up liver histol...See full text at original site
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引用元：
https://doi.org/10.1002/hep.1840100213

データ提供：米国国立医学図書館（NLM）

Chronic Hepatitis B: Course and Response to Interferon

This research explores the complex nature of chronic hepatitis B, a persistent liver infection, and investigates the effectiveness of interferon therapy in managing the disease. The study examines the natural course of the disease in patients with antibody to hepatitis B e antigen and the response to interferon treatment. It's like exploring a mysterious desert landscape, seeking to understand the patterns of a persistent illness.

Interferon Therapy: A Potential Weapon Against Hepatitis B

The study found that interferon therapy was effective in reducing hepatitis B virus DNA and improving liver function in some patients. It's like discovering a hidden spring in the desert, offering a potential source of relief for those battling this challenging infection.

Navigating the Complexity of Hepatitis B Treatment

This research underscores the complex and often unpredictable nature of hepatitis B, highlighting the need for individualized treatment strategies. It's a reminder that even in the vast and seemingly endless desert of medical research, there are new frontiers to be explored and new solutions to be discovered.

Dr.Camel's Conclusion

This study provides valuable insights into the management of chronic hepatitis B, emphasizing the need for ongoing research and tailored treatment approaches. It's a reminder that even in the most challenging medical landscapes, there are oases of hope waiting to be found.
Date :
  1. Date Completed 1989-08-17
  2. Date Revised 2019-08-28
Further Info :

Pubmed ID

2663695

DOI: Digital Object Identifier

10.1002/hep.1840100213

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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