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[Felodipine in arterial hypertension. Double-blind comparison with atenolol].

Author: AndrejakM, LesbreJ P, MorandP, Raveau-LandonC, WitchitzS

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Felodipine, a dihydropyridine calcium antagonist, effectively lowers blood pressure in hypertensive patients. In a multicenter double-blind study, felodipine and atenolol were comparable in their antihypertensive effects, with both drugs significantly lowering blood pressure. Side effects of felodipine included ankle edema and headache, while atenolol was associated with fatigue and headache.
Paper Details　
Original Abstract of the Article :
Felodipine is a new dihydropyridine calcium antagonist which selectively relaxes vascular smooth muscle. It lovers dose-dependently blood pressure in hypertensives patients. In this multicentre double-blind study, 113 patients (mean age 50 +/- 14 years) whose diastolic blood pressure was higher than...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/2675377

データ提供：米国国立医学図書館（NLM）

Felodipine vs. Atenolol for Arterial Hypertension: A Double-Blind Comparison

In the field of [cardiology], researchers are constantly evaluating the efficacy and safety of different [antihypertensive medications]. This study compares the effectiveness of [felodipine], a [calcium channel blocker], and [atenolol], a [beta-blocker], in treating [arterial hypertension]. The researchers conducted a [double-blind, multicenter trial] to assess the blood pressure-lowering effects of these medications.

Felodipine and Atenolol: Similar Antihypertensive Effects

The study's findings suggest that both [felodipine] and [atenolol] were effective in lowering blood pressure in patients with [arterial hypertension], with no significant difference in their antihypertensive effects. This research provides valuable insights into the comparative efficacy of these two commonly used medications.

Managing Hypertension: A Tailored Approach

The choice of [antihypertensive medication] is often based on individual patient characteristics and preferences. This study highlights the importance of individualized treatment plans for managing [arterial hypertension], ensuring that patients receive the most effective and well-tolerated medication for their specific needs.

Dr.Camel's Conclusion

This study is a reminder that the desert of [cardiology] is vast and complex, with many different treatment options available for [arterial hypertension]. Just as a camel navigates the desert, seeking the most suitable paths and water sources, clinicians must carefully select the most appropriate [antihypertensive medication] for each individual patient. The study's findings offer valuable insights into the comparative efficacy of [felodipine] and [atenolol], encouraging clinicians to consider a tailored approach to managing [arterial hypertension] based on individual patient needs.

Date :
  1. Date Completed 1989-10-26
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

2675377

DOI: Digital Object Identifier

2675377

SNS
PICO Info
in preparation
Languages

French

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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