Evidence on Use of Neuroimaging for Surgical Treatment of Temporal Lobe Epilepsy: A Systematic Review.

Author: CascinoGregory D, JonesAmy L

Paper Details 
Original Abstract of the Article :
IMPORTANCE: Surgery is an effective treatment for drug-resistant focal epilepsy. Neuroimaging studies are considered essential in the diagnostic evaluation of individuals with medically refractory focal seizures being considered for surgical treatment. OBJECTIVES: To review the evidence for the use...See full text at original site
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引用元:
https://doi.org/10.1001/jamaneurol.2015.4996

データ提供:米国国立医学図書館(NLM)

Neuroimaging in Temporal Lobe Epilepsy: A Guide Through the Desert of Seizure Activity

Temporal lobe epilepsy (TLE) is a chronic neurological disorder characterized by recurrent seizures. Surgery is a potential treatment option for individuals with drug-resistant TLE, but careful selection of candidates is essential for optimal outcomes. This study reviews the evidence for the use of neuroimaging techniques, including magnetic resonance imaging (MRI), positron emission tomography (PET), and single-photon emission computed tomography (SPECT), in the evaluation of patients with TLE who are being considered for surgery. The researchers analyze the prognostic importance of these techniques in predicting surgical outcomes and identify factors associated with favorable results.

Navigating the Desert of Seizure Activity: A Precise Map from Neuroimaging

The study highlights the importance of neuroimaging techniques in guiding surgical decisions for TLE. The findings suggest that MRI-identified hippocampal atrophy, consistent with mesial temporal sclerosis, is a significant factor associated with a favorable outcome after surgery. The study also emphasizes the potential value of PET imaging, particularly in individuals with unremarkable MRI findings, for identifying focal hypometabolism that could indicate seizure origin. This research provides valuable insights into the use of neuroimaging techniques for guiding surgical treatment of TLE, enhancing the precision and accuracy of surgical decisions.

A Precise Path to Recovery: Unlocking the Desert of Seizure Activity

The study underscores the importance of utilizing advanced neuroimaging techniques to precisely identify the source of seizure activity in individuals with TLE. This information is crucial for guiding surgical interventions and maximizing the likelihood of successful outcomes. The study’s findings highlight the ongoing evolution of neuroimaging in the diagnosis and treatment of epilepsy, offering new tools and strategies for navigating the desert of seizure activity and achieving better outcomes for patients.

Dr.Camel's Conclusion

This study highlights the crucial role of neuroimaging in the evaluation and treatment of TLE. The findings provide valuable insights into the prognostic importance of specific neuroimaging findings, guiding surgical decisions and enhancing the likelihood of successful outcomes for patients. The study underscores the ongoing evolution of neuroimaging techniques in the field of epilepsy, providing new tools and strategies for navigating the desert of seizure activity and achieving better outcomes for patients.

Date :
  1. Date Completed 2016-09-12
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

26926529

DOI: Digital Object Identifier

10.1001/jamaneurol.2015.4996

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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