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Does Duration of Neuropathic Pain Impact the Effectiveness of Pregabalin?

Author: AlmasMary, ClairAndrew, LatymerMark, OrtizMarie, ParsonsBruce, PérezConcepción, VarvaraRoxana

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.

Overview

Pregabalin significantly improves pain in patients with neuropathic pain regardless of the duration of pain. This was found in a pooled analysis of 19 randomized placebo-controlled trials involving 5,783 patients with neuropathic pain conditions. Pregabalin was effective in improving pain and increasing Patient Global Impression of Change (PGIC) responders in all pain duration categories, without significant differences in treatment response between these categories.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Patients with chronic pain conditions such as neuropathic pain frequently experience delays in diagnosis and treatment. Ideally, all patients should be treated in a timely manner, but in those patients with more established disease it is important to know that approved treatments remain ...See full text at original site
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引用元：
https://doi.org/10.1111/papr.12469

データ提供：米国国立医学図書館（NLM）

Pregabalin: An Effective Treatment for Neuropathic Pain, Regardless of Duration

Neuropathic pain, a chronic condition characterized by pain caused by damage to the nervous system, can be a debilitating experience. This study investigates the effectiveness of pregabalin, a medication commonly used to treat neuropathic pain, in patients with different durations of pain. The study pooled data from 19 randomized placebo-controlled trials of pregabalin, encompassing a wide range of neuropathic pain conditions, including diabetic peripheral neuropathy, postherpetic neuralgia, and post-traumatic/postsurgical pain. The study analyzed the data based on pain duration categories, allowing researchers to determine whether pregabalin's effectiveness varied depending on the length of time since the onset of pain.

Pregabalin: A Consistent and Effective Treatment Option

The study found that pregabalin significantly improved pain scores and patient-reported outcomes, regardless of the duration of pain. This finding is encouraging for individuals with long-standing neuropathic pain, suggesting that effective treatment options are available, even for those who have been experiencing pain for many years.

Finding Relief from Neuropathic Pain: A Journey of Hope

Imagine neuropathic pain as a relentless desert wind, constantly battering your body and mind. Pregabalin, like a protective oasis, offers a haven from the relentless pain, providing relief and hope for a better future. This study demonstrates that pregabalin can be an effective treatment option, regardless of the duration of pain, offering hope for individuals struggling with this challenging condition.

Dr. Camel's Conclusion

This study provides reassuring evidence that pregabalin is an effective treatment for neuropathic pain, regardless of the duration of pain. This finding offers hope for individuals with long-standing neuropathic pain, demonstrating that effective treatment options are available.

Date :
  1. Date Completed 2017-06-28
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

27589095

DOI: Digital Object Identifier

10.1111/papr.12469

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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