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Intraoperative radiation therapy (IORT) in head and neck cancer: A systematic review.

Author: BizakisIoannis, HajiioannouJiannis, KoulouliasVassilios, KyrgiasGeorge, LachanasVasileios, RapidisAlexandros, SkarlatosIoannis, SkoulakisCharalambos, ToliaMaria

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This review summarizes recent research on the use of intraoperative radiation therapy (IORT) as an adjuvant treatment for head and neck cancer. IORT offers a potential benefit by delivering a high dose of radiation directly to the tumor bed.
Paper Details　
Original Abstract of the Article :
Multimodality therapy constitutes the standard treatment of advanced and recurrent head and neck cancer. Since locoregional recurrence comprises a major obstacle in attaining cure, the role of intraoperative radiation therapy (IORT) as an add-on in improving survival and local control of the disease...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5268015/

データ提供：米国国立医学図書館（NLM）

Intraoperative Radiation Therapy (IORT) in Head and Neck Cancer: A Precision Strike Against Cancer

The fight against [head and neck cancer] often involves a multi-pronged approach. This research explores the role of [intraoperative radiation therapy (IORT)] as a powerful weapon in the arsenal of treatment options. IORT allows for a [highly targeted dose of radiation] to be delivered directly to the tumor bed, minimizing the impact on surrounding healthy tissues. This approach holds promise for improving both [local control and survival] for patients with advanced and recurrent head and neck cancer.

IORT: A Promising Adjuvant for Head and Neck Cancer Treatment

The authors conducted a [systematic review] of the literature, analyzing the evidence for using IORT as an [adjuvant therapy] for head and neck cancer. Their findings suggest that IORT can be an effective tool for [reducing the risk of locoregional recurrence] and potentially improving long-term outcomes for patients. The ability to [conformally deliver a high dose of radiation] directly to the tumor site, while sparing healthy tissues, makes IORT a compelling option for treating this complex form of cancer.

The Future of Head and Neck Cancer Treatment: Leveraging Precision Medicine

As we continue to develop new and innovative approaches to cancer treatment, [precision medicine] is gaining increasing attention. IORT represents a significant step forward in this direction, allowing for highly individualized and targeted therapies. The ability to [optimize radiation delivery] based on the specific characteristics of each patient's tumor and surrounding tissues holds great promise for improving treatment outcomes and minimizing side effects.

Dr.Camel's Conclusion

Just as the desert wind shapes the dunes, IORT can precisely shape the radiation delivery, targeting the cancer cells with precision while protecting healthy tissues. This research highlights the potential of IORT to play a vital role in the fight against head and neck cancer, and its potential for revolutionizing the field of cancer treatment through personalized medicine.

Date :
  1. Date Completed 2017-02-14
  2. Date Revised 2021-01-09
Further Info :

Pubmed ID

27977569

DOI: Digital Object Identifier

PMC5268015

SNS
PICO Info
in preparation
Languages

English

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