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Effects of a Series of Acidic Drugs on L-Lactic Acid Transport by the Monocarboxylate Transporters MCT1 and MCT4.
Author: BelangerFrancois, LeungYat H, LuJennifer, MichaudVeronique, TurgeonJacques
Original Abstract of the Article :
Drug-induced myopathy is a serious side effect that often requires removal of a medication from a drug regimen. For most drugs, the underlying mechanism of drug-induced myopathy remains unclear. Monocarboxylate transporters (MCTs) mediate L-lactic acid transport, and inhibition of MCTs may potential...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.2174/1389201019666180308091504
データ提供:米国国立医学図書館(NLM)
L-Lactic Acid Transport: A Crucial Oasis in the Desert of Muscle Function
Imagine the desert as a vast network of cells and tissues, working together to keep our bodies functioning. L-lactic acid transport is like a vital river, supplying energy to our muscles and enabling them to perform their tasks. This study is like a scientific investigation, exploring the potential impact of medications on this crucial process.The researchers investigated the effect of 24 acidic drugs on L-lactic acid transport, specifically focusing on two types of transporters, MCT1 and MCT4. They found that some of the drugs had inhibitory effects, which is like a dam blocking the flow of the river, potentially disrupting muscle function.
Drug-Induced Myopathy: Navigating the Sand Dunes of Muscle Health
This study raises concerns about the potential for certain medications to cause muscle damage, or myopathy, by interfering with L-lactic acid transport. It's like discovering a hidden sand dune that can obstruct the flow of the river, leading to problems in the desert landscape.Protecting Our Muscles: A Desert of Careful Consideration
It's important to be aware of the potential for medications to affect muscle function. This study highlights the need for careful consideration of these risks and benefits when prescribing medications, especially those that might interfere with L-lactic acid transport.Dr.Camel's Conclusion
This study is a reminder that even seemingly simple processes like L-lactic acid transport can have a significant impact on our health. It underscores the importance of understanding the potential side effects of medications and working with healthcare providers to make informed decisions about our health. Remember, even in the vast desert of our bodies, every element plays a crucial role in maintaining our well-being.Date :
- Date Completed 2018-08-17
- Date Revised 2018-12-02
Further Info :
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