Paper Details

  1. Home
  2. Paper Details

Clinical safety and efficacy of once-a-day amlodipine for chronic stable angina pectoris.

Author: GlasserS P, WestT W

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Amlodipine, a calcium channel blocker, showed both antianginal and antiischemic effects in patients with chronic stable angina pectoris. It significantly reduced anginal episodes and nitroglycerin usage. Amlodipine also improved exercise tolerance and reduced ST-segment depression during exercise tests. The drug was well tolerated and no patient withdrawals resulted from amlodipine-related adverse events.
Paper Details　
Original Abstract of the Article :
This study evaluated the safety, antianginal and antiischemic effects of amlodipine, a dihydropyridine calcium antagonist, in patients with chronic stable angina pectoris. The patients (n = 29) were evaluated during a 26-week single-blind dose titration phase followed by a 6-week double-blind placeb...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/0002-9149(88)90647-9

データ提供：米国国立医学図書館（NLM）

Amlodipine: A Safe and Effective Treatment for Angina

Chronic stable angina pectoris is a common cardiovascular condition characterized by chest pain. This study investigates the safety and efficacy of amlodipine, a calcium channel blocker, as a once-a-day treatment for chronic stable angina. The study aims to determine if amlodipine can effectively reduce anginal episodes and improve exercise tolerance in patients with this condition.

Amlodipine: A Promising Option for Angina Management

The study's findings demonstrate that amlodipine is a safe and effective treatment for chronic stable angina. The researchers found that amlodipine significantly reduced anginal episodes, improved exercise tolerance, and decreased the need for sublingual nitroglycerin. This suggests that amlodipine could be a valuable therapeutic option for patients with this condition.

Angina Management: Finding Relief in the Desert

Imagine a desert traveler experiencing chest pain, a discomfort that can be both debilitating and frightening. Amlodipine is like a refreshing spring in the desert, providing relief and improving the quality of life for individuals struggling with angina. This study's findings offer hope for patients seeking effective and safe treatment options to manage their condition.

Dr.Camel's Conclusion

This study provides compelling evidence for the effectiveness and safety of amlodipine as a once-a-day treatment for chronic stable angina. It offers a potential solution for individuals seeking to manage their condition and improve their quality of life, allowing them to navigate their lives with less discomfort and greater confidence.

Date :
  1. Date Completed 1988-10-11
  2. Date Revised 2019-06-22
Further Info :

Pubmed ID

2970788

DOI: Digital Object Identifier

10.1016/0002-9149(88)90647-9

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.