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Randomized-controlled trial of methocarbamol as a novel treatment for muscle cramps in cirrhotic patients.

Author: Abd-ElsalamSherief, ArafaMona, BadawiRehab, ElfertAsem, ElkadeemMahmoud, ElkhalawanyWalaa, SolimanShaimaa

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study evaluated the efficacy and safety of methocarbamol in controlling muscle cramps in cirrhotic patients. Methocarbamol showed a significant decrease in the frequency and duration of cramps. Few side effects of methocarbamol were recorded, including dry mouth and drowsiness.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Muscle cramps occur in 29-88% of patients with liver cirrhosis. They adversely affect quality of life. This study aimed to evaluate the efficacy and safety of methocarbamol as a novel therapy in controlling muscle cramps in cirrhotic patients. PATIENTS AND METHODS: This study was carrie...See full text at original site
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引用元：
https://doi.org/10.1097/MEG.0000000000001310

データ提供：米国国立医学図書館（NLM）

Methocarbamol: A Novel Treatment for Muscle Cramps in Cirrhosis

The debilitating condition of liver cirrhosis can lead to a range of complications, including muscle cramps. These cramps can significantly impact quality of life, often leaving patients in discomfort and limiting their mobility. This study investigates the potential of methocarbamol, a muscle relaxant, as a novel treatment for muscle cramps in patients with cirrhosis. Researchers conducted a randomized controlled trial to evaluate the efficacy and safety of methocarbamol in reducing the frequency, duration, and severity of cramps.

Promising Results for Muscle Cramp Relief

The study findings suggest that methocarbamol is a promising treatment for muscle cramps in cirrhotic patients. Patients receiving methocarbamol experienced a significant reduction in the frequency and duration of cramps, as well as a notable improvement in pain scores. These results offer hope for patients struggling with this debilitating symptom.

Navigating the Potential Benefits and Risks

While the study indicates that methocarbamol is effective and generally well-tolerated, it's essential to remember that any medication can have side effects. In this study, a few patients reported side effects such as dry mouth and drowsiness. It's crucial to discuss any potential side effects with your doctor and weigh the benefits against the risks before starting any new medication.

Dr.Camel's Conclusion

This study sheds light on a potential treatment for muscle cramps in cirrhotic patients, a condition that can significantly impact quality of life. While methocarbamol offers promise for relief, it's important to approach any new medication with caution and consult with your healthcare provider to ensure its suitability for your individual needs. Just like a desert traveler must be prepared for the unexpected, patients should be informed about the potential benefits and risks of any treatment.

Date :
  1. Date Completed 2019-06-24
  2. Date Revised 2019-06-24
Further Info :

Pubmed ID

30444744

DOI: Digital Object Identifier

10.1097/MEG.0000000000001310

SNS
PICO Info
in preparation
Languages

English

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