Comparative tolerability of two formulations of Rhinalar (flunisolide) nasal spray in patients with seasonal allergic rhinitis.

Author: GreenbaumJ, LeznoffA, MazzaJ, MillerD, SchulzJ, TobeA

Paper Details 
Original Abstract of the Article :
This double-blind, randomized, crossover study compared the incidence of nasal burning and stinging, as well as overall tolerability of the currently marketed formulation of Rhinalar (original formulation) to a new formulation of Rhinalar containing less propylene glycol. In addition, patient and in...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/3052188

データ提供:米国国立医学図書館(NLM)

Rhinalar Nasal Spray: Comparing Formulations for Seasonal Allergic Rhinitis

Seasonal allergic rhinitis, or hay fever, is a common condition that causes sneezing, runny nose, and itchy eyes. It's like a desert sandstorm, irritating the nasal passages and making it difficult to breathe. This study compared the tolerability of two formulations of Rhinalar nasal spray, a medication used to treat seasonal allergic rhinitis. The researchers aimed to determine if one formulation was better tolerated than the other, a quest like finding the most comfortable way to travel across a vast desert landscape.

Enhanced Tolerability with Reduced Propylene Glycol

The study found that the new formulation of Rhinalar, containing less propylene glycol, was significantly better tolerated than the original formulation, resulting in less nasal burning and stinging. This is like finding a camel saddle that provides a more comfortable ride across the desert. The study suggests that the new formulation could enhance patient compliance and improve the overall treatment experience.

Effective Relief from Allergy Symptoms

Both formulations were shown to be equally effective in relieving the symptoms of seasonal allergic rhinitis, providing much-needed relief from the irritating effects of pollen and other allergens. This is like finding a refreshing oasis in the midst of a sandstorm, offering respite and comfort from the harsh desert conditions. The study highlights the importance of finding the right formulation for each individual, ensuring optimal treatment and a better quality of life.

Dr.Camel's Conclusion

This study is a reminder that even the smallest details, like the formulation of a medication, can have a significant impact on patient experience. By optimizing medication formulations, we can improve treatment outcomes and create a more comfortable journey for those battling seasonal allergies.

Date :
  1. Date Completed 1988-11-04
  2. Date Revised 2021-09-01
Further Info :

Pubmed ID

3052188

DOI: Digital Object Identifier

3052188

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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