Paper Details 
Original Abstract of the Article :
Giardia lamblia, the aetiological agent of human giardiasis, is a frequently identified protozoan infection of the upper small intestine. It mainly affects children and has a wide range of clinical manifestations, from asymptomatic carriage to acute or chronic diarrhoea with dehydration, abdominal p...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/30555145

データ提供:米国国立医学図書館(NLM)

Refractory Giardiasis in Children: A Challenging Infection

Giardiasis, a parasitic infection of the small intestine, can cause a range of gastrointestinal symptoms in children. This study reports on the effectiveness of a combination therapy using secnidazole and albendazole in treating drug-refractory giardiasis in children. The authors analyze data from a case series, evaluating the clinical response and tolerability of this treatment approach.

Secnidazole Plus Albendazole: A Potential Treatment Option

The study's findings suggest that the combination of secnidazole and albendazole may be a viable treatment option for drug-refractory giardiasis in children. The authors observed a high cure rate (82%) in a group of 11 patients who had previously failed conventional treatments. The treatment combination was well-tolerated, with only mild and transient side effects reported. These results encourage further investigation into the use of this combination therapy for challenging cases of giardiasis.

Fighting Parasitic Infections: A Collaborative Approach

The study's findings highlight the importance of developing effective treatment strategies for parasitic infections. The authors' case series demonstrates the potential of combination therapy to overcome resistance and improve treatment outcomes. This study encourages continued research into novel treatment options for giardiasis, seeking to minimize the impact of this common parasitic infection on children's health.

Dr. Camel's Conclusion

Just as a camel can adapt to survive in a harsh desert environment, children with giardiasis may require a multi-pronged approach to overcome this persistent infection. This research offers valuable insights into the potential of combination therapy, providing hope for a future where giardiasis can be more effectively managed.

Date :
  1. Date Completed 2019-06-25
  2. Date Revised 2019-08-16
Further Info :

Pubmed ID

30555145

DOI: Digital Object Identifier

30555145

SNS
PICO Info
in preparation
Languages

English

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