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Intra-articular injections of platelet-rich plasma, hyaluronic acid or corticosteroids for knee osteoarthritis : A prospective randomized controlled study.

Author: HuangYong, LiuJunbin, LiuXiaolu, XuXinliang

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Knee osteoarthritis (KOA) is a painful condition with no cure. While there are various treatments for KOA, injections into the joint (intra-articular therapies) are increasingly used, including platelet-rich plasma (PRP), hyaluronic acid (HA), and corticosteroids (CS).
Paper Details　
Original Abstract of the Article :
Knee osteoarthritis (KOA) is a degenerative joint disease leading to pain and disability for which no curative treatment exists. Intra-articular (IA) therapies are part of this multimodal approach and are approved by the Food and Drug Administration (FDA) and European Medicines Agency (EMA). Platele...See full text at original site
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引用元：
https://doi.org/10.1007/s00132-018-03659-5

データ提供：米国国立医学図書館（NLM）

Knee Osteoarthritis: Navigating the Sands of Pain and Disability

The desert of [knee osteoarthritis (KOA)] can be a challenging landscape, causing pain and disability for many individuals. This research explores the effectiveness of [intra-articular (IA) injections] of [platelet-rich plasma (PRP), hyaluronic acid (HA), and corticosteroids (CS)] as treatments for KOA. Utilizing [a prospective randomized controlled study], the researchers compared the outcomes of these three therapies in a cohort of patients with KOA.

Seeking Relief in the Oasis of KOA

The study's findings indicate that while all three treatments showed some level of improvement, [PRP] demonstrated [the most significant benefit] in reducing pain and improving function. This suggests that PRP might offer a more effective approach to managing KOA compared to HA and CS.

Navigating the Sands of KOA Treatment

As a desert wanderer, I urge caution in interpreting these findings. Each individual's response to these treatments may vary, and it's crucial to consult a qualified healthcare professional for personalized advice and treatment options. It's also important to note that these therapies are not a cure for KOA, but they can provide significant relief from pain and disability.

Dr. Camel's Conclusion

Intra-articular injections of platelet-rich plasma show promising results for managing knee osteoarthritis, offering potential benefits in reducing pain and improving function. However, individual responses may vary, and personalized treatment options should be discussed with a healthcare professional.

Date :
  1. Date Completed 2019-09-20
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

30623236

DOI: Digital Object Identifier

10.1007/s00132-018-03659-5

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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