Immunogenicity and side-effects of the inactivated hepatitis A vaccine in periodic fever, aphthous stomatitis, pharyngitis, and adenitis patients.

Author: DiamantopoulosStavros, MaritsiDespoina N, SyrmouAreti, TsoliaMaria N, VartzelisGeorge

Paper Details 
Original Abstract of the Article :
The aim of this study was to compare the immunogenicity and side-effects of hepatitis A virus (HAV) vaccination between periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) patients and healthy controls who have not been previously exposed to HAV. A prospective observational study ...See full text at original site
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引用元:
https://doi.org/10.1111/ped.13719

データ提供:米国国立医学図書館(NLM)

Hepatitis A Vaccine: A Safe and Effective Journey for PFAPA Patients

Periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) is a recurring inflammatory disorder affecting children. It's like a desert sandstorm, recurring with unpredictable frequency and intensity. This study investigates the immunogenicity and safety of the inactivated hepatitis A vaccine in PFAPA patients, examining its effectiveness in this unique patient population. It's like a camel caravan, carefully navigating a treacherous desert, ensuring the safety and well-being of its travelers while achieving its destination.

A Safe and Effective Journey

The research found that two doses of the inactivated hepatitis A vaccine are well-tolerated and effective in children with PFAPA. It's like a safe passage through the desert, where travelers are protected from the harsh elements while successfully reaching their destination. The authors observed robust seroconversion and seroprotection rates, suggesting that the vaccine provides effective protection against hepatitis A in these patients. It's like a desert oasis, where travelers find refuge and protection from the harsh environment.

Protecting Children from Hepatitis A

These findings offer reassurance for healthcare providers managing PFAPA patients. It's like a reliable compass, guiding the way to protect children from the dangers of hepatitis A. The study demonstrates the effectiveness of the hepatitis A vaccine in this population, emphasizing the importance of timely vaccination to protect children from this potentially serious disease. It's like building a sturdy shelter in the desert, providing a safe haven from the unpredictable elements.

Dr. Camel's Conclusion

This study provides encouraging news for children with PFAPA, demonstrating the safety and effectiveness of the inactivated hepatitis A vaccine. It's like a desert oasis, offering a safe haven and a promise of protection against the unpredictable elements. By understanding the vaccine's efficacy in this unique population, healthcare providers can ensure the well-being of children with PFAPA and protect them from the potential dangers of hepatitis A.

Date :
  1. Date Completed 2019-02-22
  2. Date Revised 2019-02-22
Further Info :

Pubmed ID

30734430

DOI: Digital Object Identifier

10.1111/ped.13719

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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