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Evaluation of Drinking Risk Levels as Outcomes in Alcohol Pharmacotherapy Trials: A Secondary Analysis of 3 Randomized Clinical Trials.
Author: , AntonRaymond F, FalkDaniel E, FertigJoanne, HasinDeborah S, JohnsonBankole, KranzlerHenry R, LittenRaye Z, MannKarl F, MeulienDidier, O'MalleyStephanie S, RyanMegan, SlaterMegan, WitkiewitzKatie
Original Abstract of the Article :
The US Food and Drug Administration recognizes total abstinence and no heavy drinking days as outcomes for pivotal pharmacotherapy trials for alcohol use disorder (AUD). Many patients have difficulty achieving these outcomes, which can discourage seeking treatment and has slowed the development of m...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450273/
データ提供:米国国立医学図書館(NLM)
Redefining Success: Evaluating Drinking Risk Levels in Alcohol Pharmacotherapy Trials
The journey towards recovery from alcohol use disorder (AUD) is often marked by setbacks and relapses. This study, like a meticulous scholar examining historical records, delves into the complexities of measuring success in alcohol pharmacotherapy trials. The authors, with the keen observation of a seasoned desert traveler, challenge traditional outcome measures, highlighting the need for a more nuanced assessment of drinking risk levels.
The US Food and Drug Administration (FDA) currently recognizes total abstinence and no heavy drinking days as key outcomes for evaluating the effectiveness of medications for AUDs. However, this study, like a desert oasis offering alternative perspectives, argues that these measures may not fully capture the realities of recovery, often leading to unrealistic expectations and discouraging patients from seeking treatment.
A Broader Perspective: Beyond Abstinence and Heavy Drinking Days
This study proposes a shift in focus, urging researchers to consider a broader spectrum of drinking risk levels, including reduced consumption and fewer heavy drinking days, as meaningful outcomes in pharmacotherapy trials. This approach, like a desert bloom defying the harsh conditions, acknowledges the challenges of achieving complete abstinence and recognizes the value of incremental progress.
A More Compassionate Approach: Supporting Individual Goals and Recovery Journeys
This study, like a compassionate guide offering support during a challenging journey, calls for a more humane and patient-centered approach to evaluating alcohol pharmacotherapy. By acknowledging the complexities of AUDs and recognizing the value of individual progress, we can better support patients on their path to recovery.
Dr. Camel's Conclusion
Recovery from AUDs is a complex and individualized journey. This study challenges us to move beyond simplistic measures of success and adopt a more compassionate and nuanced approach to evaluating treatment outcomes. By embracing a broader perspective and acknowledging the value of individual progress, we can create a more supportive and effective system for those seeking help with AUDs.
Date :
- Date Completed 2020-02-14
- Date Revised 2022-07-16
Further Info :
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