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Cognitive and behavioral findings in children taking theophylline.

Author: BiermanC W, DuHamelT R, FurukawaC T, PiersonW E, ShapiroG G, WeimerL

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study compared the effects of theophylline and cromolyn sodium on memory, concentration, and behavior in 29 children with asthma. The group receiving placebo theophylline/active cromolyn sodium showed greater improvement in all tests of memory and concentration. The study also raised concerns about depression and anxiety as potential long-term side effects of theophylline.
Paper Details　
Original Abstract of the Article :
In a prior pilot study involving six children, we noted improved memory and concentration and improved behavior when these children were switched from theophylline to cromolyn sodium therapy. We now report the findings in 29 children (24 boys and five girls), aged 7 to 12 years. In this study, a dou...See full text at original site
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引用元：
https://doi.org/10.1016/0091-6749(88)90224-2

データ提供：米国国立医学図書館（NLM）

Theophylline's Impact on Cognitive and Behavioral Development in Children

The study of [children's cognitive development], like exploring the intricate growth patterns of a desert ecosystem, requires a careful and sensitive approach. This study examines the potential effects of [theophylline], a medication commonly used to treat [asthma], on the cognitive and behavioral development of children. The researchers, like dedicated desert ecologists, carefully studied a group of children, comparing those receiving [theophylline] with those switched to alternative therapies.

Potential Cognitive and Behavioral Side Effects

The study's findings raise concerns about the potential impact of [theophylline] on [cognitive function] in children. The authors, like astute observers of a delicate desert ecosystem, noted that children receiving [theophylline] exhibited poorer performance on tests of [memory and concentration]. Additionally, the study suggests a possible link between prolonged [theophylline] use and increased risks of [depression and anxiety] in children.

Navigating the Treatment Landscape

This study underscores the importance of carefully weighing the risks and benefits of [theophylline] therapy in children. As with navigating a vast desert, it's crucial to understand the potential challenges and have a plan in place to address them. Healthcare professionals must consider individual factors and carefully monitor for potential side effects while seeking alternative therapies when appropriate.

Dr. Camel's Conclusion

This study, like a warning sign in a desert landscape, highlights the potential risks of [theophylline] therapy in children. The authors, like keen desert observers, have uncovered evidence of potential cognitive and behavioral side effects associated with [theophylline] use. This study emphasizes the need for cautious use and ongoing monitoring to ensure the well-being of children receiving this medication.

Date :
  1. Date Completed 1988-03-18
  2. Date Revised 2019-07-23
Further Info :

Pubmed ID

3123538

DOI: Digital Object Identifier

10.1016/0091-6749(88)90224-2

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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