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Non-specific effects of MMR vaccines on infectious disease related hospitalizations during the second year of life in high-income countries: a systematic review and meta-analysis.

Author: HarderThomas, SiedlerAnette, SinzingerAndrea Xaver, Von KriesRüdiger, WichmannOle

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This study reviewed the evidence regarding the potential benefit of MMR vaccination on the risk of hospitalization due to infectious diseases. The available evidence is insufficient to support a change in current vaccination schedules.
Paper Details　
Original Abstract of the Article :
Children who had received MMR as the most recent vaccine had a pooled 35% (95%CI: 12-53%) lower risk for hospitalization due to any infectious disease, compared to children who had received DTaP as the most recent vaccine (three studies, 1,919,192 children). The effect was stronger for respiratory t...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227673/

データ提供：米国国立医学図書館（NLM）

MMR Vaccine: More Than Just Measles, Mumps, and Rubella Protection

The field of [vaccination] is constantly striving to [understand the full impact] of [different vaccines] on [child health]. This study investigates the [non-specific effects of MMR vaccines] on [infectious disease-related hospitalizations] in [high-income countries]. The researchers analyzed data from [three studies involving over 1.9 million children], finding that [children who had received MMR as the most recent vaccine had a significantly lower risk of hospitalization due to any infectious disease] compared to those who had received [DTaP as the most recent vaccine]. While the study acknowledges [methodological limitations and the need for further research], it suggests a [possible broader protective effect of MMR vaccines] beyond their [intended targets of measles, mumps, and rubella].

Exploring the Benefits of MMR Vaccines

This research expands our understanding of [the protective effects of MMR vaccines], suggesting that [they might offer broader protection against a range of infectious diseases]. The researchers found that [MMR vaccination was associated with a reduced risk of hospitalization for respiratory and gastrointestinal infections], highlighting the [potential public health benefits] of [high vaccination rates] and [promoting herd immunity].

Understanding the Importance of Vaccination

It's crucial to [adhere to recommended vaccination schedules] for your children to [protect them from preventable diseases]. This research provides evidence for [the potential benefits of MMR vaccines beyond their intended targets], suggesting that [they may play a broader role in strengthening the immune system] and [reducing the risk of infectious diseases]. By [embracing vaccination] and [promoting herd immunity], we can [create a healthier society] for everyone.

Dr. Camel's Conclusion

Just as a camel's immune system adapts to the harsh desert environment, this research explores how MMR vaccines might offer broader protection beyond their intended targets. By understanding the full potential of vaccines, we can create a more resilient and healthy world for all.

Date :
  1. Date Completed 2021-06-21
  2. Date Revised 2021-06-21
Further Info :

Pubmed ID

31625797

DOI: Digital Object Identifier

PMC7227673

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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