Paper Details

  1. Home
  2. Paper Details

Hypersensitivity and adverse reactions to biologics for asthma and allergic diseases.

Author: BahnaSami L, JacksonKim

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This review article discusses the adverse effects (AE) of five biologics approved for asthma and/or allergic diseases: omalizumab, mepolizumab, reslizumab, benralizumab, and dupilumab.
Paper Details　
Original Abstract of the Article :
<b>Introduction</b>: The development of new biologic agents has provided definite therapeutic advances but, like with any new medications, safety remains a concern.<b>Areas covered</b>: Using PubMed, we reviewed the literature on the adverse effects (AE) to five biologics approved for asthma and/or...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1080/1744666X.2020.1724089

データ提供：米国国立医学図書館（NLM）

Navigating the Desert of Biologics: A Guide to Hypersensitivity and Adverse Reactions

This research explores the safety profile of biologic agents, a new class of medications that have revolutionized the treatment of asthma and allergic diseases. The study reviews the literature on the adverse effects of five key biologics, including one anti-IgE (omalizumab), three anti-IL5 (mepolizumab, reslizumab, benralizumab), and one anti-IL4 (dupilumab), providing valuable insights into their potential risks and benefits.

Exploring the Uncharted Terrain of Biologics

This research provides a roadmap through the uncharted terrain of biologics, highlighting the potential for hypersensitivity and adverse reactions. While these medications offer significant therapeutic advantages, it is crucial to be aware of their potential side effects to ensure safe and effective treatment.

Understanding the Risks and Benefits of Biologics

This review underscores the importance of understanding both the risks and benefits of biologics. The study provides valuable information for healthcare professionals and patients alike, enabling them to make informed decisions about these revolutionary new treatments.

Dr. Camel's Conclusion

The desert of biologic therapy is vast and holds both promise and potential pitfalls. This research serves as a guide through this challenging landscape, providing insights into the potential for hypersensitivity and adverse reactions. By understanding these risks, we can ensure the safe and effective application of these life-changing medications.

Date :
  1. Date Completed 2021-06-28
  2. Date Revised 2021-06-28
Further Info :

Pubmed ID

31994421

DOI: Digital Object Identifier

10.1080/1744666X.2020.1724089

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.