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Bullous pemphigoid associated with the use of dipeptidil peptidase-4 inhibitors: analysis from studies based on pharmacovigilance databases.

Author: GarcíaPilar, MartinLuis H, Molina-GuarnerosJuan A, Navarro-GarcíaEster, Rodríguez-JiménezPedro, Sainz-GilMaría, Sanz-FadriqueRosario

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study found evidence of an association between dipeptidase-4 inhibitors and bullous pemphigoid, a rare autoimmune skin disease. The association was statistically significant for both the pharmacological class as a whole and each of the individual dipeptidase-4 inhibitors agents under investigation.
Paper Details　
Original Abstract of the Article :
Background Bullous pemphigoid has been associated to dipeptidase-4 inhibitors. Objectives Addressing the potential Bullous pemphigoid-dipeptidase-4 inhibitors association based on pharmacovigilance data currently available in Spain in order to obtain a composite disproportionality estimator from all...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192859/

データ提供：米国国立医学図書館（NLM）

Dipeptidyl Peptidase-4 Inhibitors and Bullous Pemphigoid: A Desert of Unexpected Reactions

Dipeptidyl peptidase-4 (DPP-4) inhibitors, like a desert oasis, offer potential benefits for managing type 2 diabetes. However, this research investigates a potential side effect of these medications, bullous pemphigoid, a blistering skin condition. The researchers, like skilled desert explorers, sought to uncover the connection between DPP-4 inhibitors and bullous pemphigoid.

Navigating the Dunes of Potential Side Effects

The research, like a careful study of desert plants, examines the association between DPP-4 inhibitors and bullous pemphigoid. The findings, like a warning sign in the desert, reveal a statistically significant association between these medications and the development of bullous pemphigoid. This research, like a compass guiding us through the desert of drug safety, provides valuable insights into the potential risks associated with DPP-4 inhibitors.

A Reminder of Potential Risks

This research highlights the importance of monitoring for potential side effects with any medication. The findings, like a cool breeze in the desert, emphasize the need for continued vigilance and careful observation when prescribing DPP-4 inhibitors. This research, like a beacon in the desert of drug safety, underscores the importance of understanding the potential risks and benefits of all medications.

Dr. Camel's Conclusion

This research investigates the potential association between dipeptidyl peptidase-4 (DPP-4) inhibitors and bullous pemphigoid. The findings reveal a statistically significant association between these medications and the development of this blistering skin condition. This research, like a compass guiding us through the desert of drug safety, highlights the importance of monitoring for potential side effects and underscores the need for careful consideration when prescribing DPP-4 inhibitors.
Date :
  1. Date Completed 2021-03-04
  2. Date Revised 2021-09-20
Further Info :

Pubmed ID

32140915

DOI: Digital Object Identifier

PMC7192859

SNS
PICO Info
in preparation
Languages

English

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