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Methylphenidate Effects on Cortical Thickness in Children and Adults with Attention-Deficit/Hyperactivity Disorder: A Randomized Clinical Trial.

Author: AmlienI, BjørnerudA, FjellA M, GrooteI, RenemanL, RohaniD A, SchranteeA, WalhovdK B

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Methylphenidate, a common treatment for attention-deficit/hyperactivity disorder, had different effects on cortical thickness in children and adults. The findings suggest that the drug may affect gray matter development in the right medial cortex. Further research is needed to confirm these findings and investigate potential long-term consequences.
Paper Details　
Original Abstract of the Article :
BACKGROUND AND PURPOSE: Although methylphenidate is frequently used to treat children with attention-deficit/hyperactivity disorder, it is currently unknown how methylphenidate affects brain development. In a randomized controlled trial, we investigated whether the cortical effects of methylphenidat...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228175/

データ提供：米国国立医学図書館（NLM）

Methylphenidate: A Tale of Two Ages in ADHD Treatment

Methylphenidate is a commonly prescribed medication for attention-deficit/hyperactivity disorder (ADHD). This study investigated the effects of methylphenidate on cortical thickness in children and adults with ADHD. The researchers conducted a randomized controlled trial to examine the impact of methylphenidate on brain development in different age groups.

Methylphenidate: A Brain-Altering Journey

The study found that methylphenidate had different effects on cortical thickness in children and adults with ADHD. The researchers observed a significant interaction between age, medication, and time, suggesting that methylphenidate’s effects on brain development may vary depending on age.

Navigating the Desert of ADHD Research: A Search for Answers

Just as a camel needs to find its way across the vast desert, understanding the complexities of ADHD requires careful research and exploration. This study provides valuable insights into the potential effects of methylphenidate on brain development in different age groups. Remember, ongoing research is crucial for developing effective and safe treatments for ADHD, especially considering the potential impact of medications on brain development.

Dr.Camel's Conclusion

This study provides a fascinating glimpse into the complex interplay of age, medication, and brain development in ADHD. The findings highlight the importance of considering the potential long-term effects of methylphenidate, particularly in children. Further research is needed to fully understand the impact of this medication on brain development and to optimize treatment strategies for ADHD.

Date :
  1. Date Completed 2020-11-09
  2. Date Revised 2021-05-02
Further Info :

Pubmed ID

32414901

DOI: Digital Object Identifier

PMC7228175

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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