Comparative efficacies of erythromycin-sulfisoxazole and cefaclor in acute otitis media: a double blind randomized trial.

Author: AhronheimG, BergeronM G, BouchardM, BryerD, CronC, DempseyE E, MacdonaldN, RichardJ E, RidingK, YoungJ

Paper Details 
Original Abstract of the Article :
A prospective double blind trial compared the fixed combination of erythromycin-sulfisoxazole (E/S) with cefaclor in the treatment of acute otitis media. One hundred nineteen children in six centers across Canada were studied. Diagnostic tympanocentesis of 134 ears yielded 135 bacterial isolates: St...See full text at original site
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引用元:
https://doi.org/10.1097/00006454-198707000-00007

データ提供:米国国立医学図書館(NLM)

Acute Otitis Media: A Battleground for Antibiotics

Acute otitis media, a common ear infection, often leaves little ones feeling miserable. This study, a foray into the dusty battlefield of ear infections, compares the effectiveness of two antibiotic treatments: erythromycin-sulfisoxazole (E/S) and cefaclor. The researchers, like intrepid explorers venturing into uncharted territory, conducted a double-blind randomized trial to assess the efficacy of these treatments in a group of children with acute otitis media. Their findings: E/S emerged as a strong contender, demonstrating effectiveness comparable to cefaclor and potentially offering faster symptom relief.

A New Champion in the Fight Against Ear Infections

This study's results, like a refreshing oasis in a parched desert, suggest that E/S may be a viable alternative to cefaclor in treating acute otitis media. The researchers observed a significant difference in the rate of complete cure for patients with negative bacterial cultures, suggesting that E/S might be particularly beneficial in these cases. This finding highlights the importance of considering individual patient characteristics when selecting antibiotics for ear infections.

Navigating the Ear Infection Desert

This study, like a map leading us through the intricacies of ear infections, provides valuable insights into the effectiveness of different antibiotic treatments. While E/S showed promise in this study, it's crucial to consult with healthcare professionals for personalized recommendations based on individual needs. Further research, like a caravan of scientists seeking knowledge, will continue to unravel the mysteries of ear infections and help us develop better treatments for all patients.

Dr.Camel's Conclusion

This study provides a comprehensive comparison of two antibiotic treatments for acute otitis media. The findings suggest that E/S may be a valuable alternative to cefaclor, especially for patients with negative bacterial cultures. However, personalized treatment decisions are essential.

Date :
  1. Date Completed 1987-09-15
  2. Date Revised 2019-08-18
Further Info :

Pubmed ID

3302918

DOI: Digital Object Identifier

10.1097/00006454-198707000-00007

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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