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Is there a correlation between hypomagnesemia linked to long-term proton pump inhibitor use and the active agent?
Author: AkarsuMurat, Aydın YoldemirŞengül, OzcanMustafa, Zeren OzturkGuzin
Original Abstract of the Article :
BACKGROUND: One of the electrolyte disorders considered to be linked to proton pump inhibitors (PPI) use is hypomagnesemia. The aim of this study was to assess the incidence of hypomagnesemia linked to long-term PPI use and the correlation with active agents. METHODS: The study included 305 patient...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1007/s00508-021-01834-x
データ提供:米国国立医学図書館(NLM)
Proton Pump Inhibitors and Hypomagnesemia: A Tale of Two Active Agents
In the vast desert of gastrointestinal health, researchers are constantly searching for the hidden oases of optimal well-being. This study delves into the intricate relationship between proton pump inhibitors (PPIs) and a condition known as hypomagnesemia, where magnesium levels in the blood dip below the healthy range. The study, using a survey approach, aimed to assess the occurrence of hypomagnesemia linked to long-term PPI use and its correlation with specific active agents. The findings suggest that hypomagnesemia is indeed linked to PPI use, and the type of PPI matters. The study found that while some PPIs, like rabeprazole, were associated with lower rates of hypomagnesemia, omeprazole, a commonly prescribed PPI, was linked to significantly higher rates. The study also revealed a clear correlation between age and duration of PPI use with the risk of developing hypomagnesemia. These findings are particularly noteworthy as they emphasize the importance of carefully considering the potential risks associated with long-term PPI use, especially in individuals who are older or have been taking PPIs for extended periods.
Omeprazole: A Case for Caution
The results of this study have profound implications for patient care. It underscores the need for meticulous monitoring of magnesium levels in patients on long-term PPIs, particularly those using omeprazole. The researchers emphasize the need for vigilant monitoring of magnesium levels in those taking PPIs for a prolonged period, especially omeprazole. The study's findings are a reminder that even seemingly benign medications can have unexpected consequences when used long-term.
Protecting Your Inner Oasis
As a fellow traveler in the desert of health, I encourage you to approach your medications with a discerning eye, particularly when it comes to long-term use. If you're taking PPIs, it's crucial to have open and honest conversations with your doctor about the potential risks and benefits. Regular magnesium checks can help you stay ahead of any potential issues. Remember, like a desert traveler, it's important to be aware of your surroundings and take proactive measures to safeguard your health.
Dr.Camel's Conclusion
This research emphasizes the importance of careful consideration of the potential risks associated with long-term PPI use, particularly omeprazole. The desert of health is full of hidden dangers, but with vigilance and informed decisions, we can navigate its treacherous paths and preserve our inner oasis of well-being.
Date :
- Date Completed 2022-02-22
- Date Revised 2022-05-31
Further Info :
English
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