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Efficacy of intra-articular corticosteroid injections in knee osteoarthritis: A systematic review and meta-analysis of randomized controlled trials.

Author: AlunnoAlessia, BerenbaumFrancis, GwinnuttJames M, NajmAurélie, WeillCatherine

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

IA GC injections reduced pain and improved function early after administration compared to placebo. Other interventions seem to be more efficient in the long term, but this effect was largely driven by single studies with large effect sizes.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: Knee osteoarthritis (OA) is a frequent degenerative disease representing an important health and economic burden. Symptomatic medical treatments available include intra-articular (IA) injections of corticosteroids (GC) but their efficacy and safety profile are debated. METHODS: We perfor...See full text at original site
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引用元：
https://doi.org/10.1016/j.jbspin.2021.105198

データ提供：米国国立医学図書館（NLM）

Corticosteroid Injections for Knee Osteoarthritis: A Temporary Oasis?

Knee osteoarthritis (OA), a degenerative condition, can cause significant pain and discomfort. This study investigates the efficacy of intra-articular (IA) corticosteroid injections for knee OA. The researchers conducted a systematic review and meta-analysis of randomized controlled trials to assess the short-term and long-term effects of these injections on pain and function. The results offer a nuanced understanding of the benefits and limitations of corticosteroid injections for knee OA.

Corticosteroid Injections: A Short-Term Solution for Knee Pain

The meta-analysis found that IA corticosteroid injections provided a temporary reduction in pain and improved function in the short term (≤6 weeks) compared to placebo. This suggests that these injections can provide temporary relief from knee pain, acting like a refreshing oasis in the desert of OA symptoms. However, the effects were not sustained in the long term, and other interventions might be more effective over time.

Knee Osteoarthritis Management: A Multifaceted Approach

This study underscores the importance of a multifaceted approach to managing knee OA. While corticosteroid injections can provide short-term relief, long-term management may require a combination of strategies, including physiotherapy, weight management, and other non-pharmacological interventions. It's like creating a network of oases in the desert of OA, offering a more sustainable and comprehensive approach to managing this chronic condition.

Dr.Camel's Conclusion

This meta-analysis highlights the short-term benefits of intra-articular corticosteroid injections for knee osteoarthritis, providing temporary relief from pain and improved function. However, the study also emphasizes the need for long-term management strategies that address the underlying causes of OA, potentially leading to more sustained improvements in quality of life for individuals with this condition.

Date :
  1. Date Completed 2021-06-25
  2. Date Revised 2021-06-25
Further Info :

Pubmed ID

33901659

DOI: Digital Object Identifier

10.1016/j.jbspin.2021.105198

SNS
PICO Info
in preparation
Languages

English

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