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Non-specific effects of rabies vaccine on the incidence of self-reported common infectious disease episodes: A randomized controlled trial.

Author: BarryDonna, BatticeJuliet, ConanAnne, EnglandShianne, GessnerBradford D, KnobelDarryn L, OditaChristianah I, Smith-AntonyMarshalette

Clinical Trial, Phase IVPost-marketing surveillance. Monitors long-term safety/efficacy after approval.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This randomized controlled trial investigated whether a rabies vaccine could protect against other common infections. The results showed no significant difference in the incidence of common infections between vaccinated and unvaccinated participants. This suggests that the rabies vaccine does not offer broad protection against other infections.
Paper Details　
Original Abstract of the Article :
Vaccines may affect recipients' immune systems in ways that change morbidity or mortality rates to unrelated infections in vaccinated populations. It has been proposed that these non-specific effects differ by type of vaccine and by sex, with non-live vaccines enhancing susceptibility of females to ...See full text at original site
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引用元：
https://doi.org/10.1016/j.vaccine.2021.06.007

データ提供：米国国立医学図書館（NLM）

The Mystery of Rabies Vaccine and Other Infections

Vaccines are our trusty camels, helping us navigate the desert of infectious diseases. But what about their impact on other infections? This study investigated whether the rabies vaccine, a non-live vaccine, could affect the incidence of common infectious diseases in a population of veterinary students. The researchers are exploring the potential for non-specific effects, like discovering hidden springs of immunity or unexpected side effects in the desert of vaccines.

The study found that the rabies vaccine did not significantly affect the incidence of common infectious diseases. It's like finding a hidden oasis, but one that doesn't offer any special protection against other desert dangers.

Unveiling the Oasis: Rabies Vaccine and Common Infections

This research delves into the complex relationship between vaccines and the immune system. It's like exploring a hidden oasis, a rich ecosystem with intricate interactions. The study found that while the rabies vaccine provides protection against rabies, it doesn't seem to offer additional protection against common infections. It's like discovering that the oasis is a haven for some animals but not for others.

The study's findings are important for understanding the specific effects of vaccines. It's like recognizing that each oasis has its own unique characteristics and benefits. Further research is needed to understand the full spectrum of a vaccine's impact on the immune system.

Dr.Camel's Conclusion

This study reminds us that vaccines are not a magic bullet for all infections. While the rabies vaccine protects against rabies, it doesn't seem to offer additional protection against other common illnesses. This research provides valuable insights into the specific effects of vaccines and emphasizes the importance of continued research to better understand their role in maintaining overall health.

Date :
  1. Date Completed 2022-03-10
  2. Date Revised 2022-03-11
Further Info :

Pubmed ID

34127294

DOI: Digital Object Identifier

10.1016/j.vaccine.2021.06.007

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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