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Antibiomania: a case report of clarithromycin and amoxicillin-clavulanic acid induced manic episodes separately.

Author: AmbrosettiJulia, BessonMarie, BondolfiGuido, CostanzaAlessandra, MeszarosEdith Paula, SarasinFrançois, StancuCatheline

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

A brief manic episode was suspected to be induced by clarithromycin and amoxicillin-clavulanic acid in a patient with no psychiatric history. Early recognition and intervention are crucial for managing psychiatric side effects related to antibiotics.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Antibiomania is a rare but recognized side effect with yet unclear definite pathogenesis although multiple hypotheses have been proposed. The novelty of this case is the suspected pharmacodynamic drug-drug interaction between clarithromycin and amoxicillin-clavulanic acid. CASE PRESENTA...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359544/

データ提供：米国国立医学図書館（NLM）

Antibiomania: A Case Report of Unexpected Side Effects

The world of medicine is often filled with surprises. This case report delves into the intriguing phenomenon of antibiomania, a rare but recognized side effect of antibiotic therapy. The authors present a case of a patient who experienced manic episodes after taking both clarithromycin and amoxicillin-clavulanic acid, highlighting the unexpected challenges of antibiotic therapy.

The Shifting Sands of Antibiotic Therapy

This case report underscores the potential for unexpected side effects from seemingly innocuous medications. Antibiomania highlights the need for vigilance and careful monitoring of patients, especially those with pre-existing psychiatric conditions. It also emphasizes the importance of further research to understand the mechanisms behind this phenomenon and to develop strategies for preventing and managing this unexpected side effect.

Navigating the Desert of Antibiotic Therapy

As we journey through the desert of antibiotic therapy, it's essential to be aware of the potential for unexpected side effects. This case report serves as a reminder to physicians to be vigilant and to closely monitor patients for any signs of mental health changes. Additionally, it highlights the importance of exploring alternative therapies when possible, minimizing the risk of adverse events.

Dr.Camel's Conclusion

This case report serves as a reminder that even in the seemingly predictable desert of antibiotic therapy, unexpected oases of side effects can emerge. The authors' observation of antibiomania highlights the importance of careful monitoring and the need for continued research to understand the complex interactions between medications and the human body.

Date :
  1. Date Completed 2021-08-26
  2. Date Revised 2021-08-26
Further Info :

Pubmed ID

34380446

DOI: Digital Object Identifier

PMC8359544

SNS
PICO Info
in preparation
Languages

English

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