Paper Details

  1. Home
  2. Paper Details

Randomized Clinical Trials on the Efficacy and Safety of Tocilizumab in Subjects with Rheumatoid Arthritis: A Systematic Review.

Author: Al AmoodiAbdulla, Al MazroueiNadia, AlkaabiMaisoun, BarakaMohamed A, DonJudit, ElnourAsim Ahmed, FarahFarah Hamad, KidirIsraa Yousif, RamadanAzza, SadeqAdel

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Tocilizumab (TCZ) is an effective treatment for rheumatoid arthritis (RA), reducing disease activity and improving disability. TCZ may be associated with increased cholesterol levels but does not appear to increase the risk of serious adverse events.
Paper Details　
Original Abstract of the Article :
BACKGROUND: The current therapy of Rheumatoid Arthritis (RA) is confronted with many challenges such as inadequate response, infection, and treatment failure. AIM AND OBJECTIVE: The main objective was to assess the efficacy and safety of tocilizumab (TCZ) in subjects with RA using the available evi...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.2174/2772432817666220202115623

データ提供：米国国立医学図書館（NLM）

Tocilizumab: A Comprehensive Review of its Efficacy and Safety in Rheumatoid Arthritis

This systematic review examines the effectiveness and safety of [tocilizumab (TCZ)] in the management of [rheumatoid arthritis (RA)]. The authors analyzed data from nine [randomized controlled trials] involving [4129 patients] with [RA]. The study found that [TCZ] was significantly effective in reducing [disease activity] and improving [disability] in patients with [RA]. While [TCZ] was generally well-tolerated, the review highlights the need for ongoing monitoring of potential side effects, particularly [lipid profile] changes.

Tocilizumab: A Powerful Tool in the Arsenal Against Rheumatoid Arthritis

This systematic review offers a comprehensive overview of the efficacy and safety of [tocilizumab (TCZ)] in managing [rheumatoid arthritis (RA)]. The findings clearly demonstrate the effectiveness of [TCZ] in reducing [disease activity] and improving [disability] in patients with [RA]. The review also highlights the importance of ongoing monitoring for potential side effects, particularly [lipid profile] changes, to ensure the safe and effective use of this medication.

The Journey Through Rheumatoid Arthritis: A Guide to Effective Management

Living with [rheumatoid arthritis (RA)] can be a challenging journey, filled with pain and limitations. This research offers valuable insights into the effectiveness and safety of [tocilizumab (TCZ)] as a treatment option for [RA]. Remember, working closely with your healthcare provider and participating in clinical trials can help ensure the best possible outcomes and navigate the complexities of managing [RA].

Dr.Camel's Conclusion

This systematic review is like a compass, guiding us through the vast desert of [rheumatoid arthritis (RA)] research. The authors have meticulously analyzed the evidence, showcasing the potential of [tocilizumab (TCZ)] as a valuable treatment option for [RA]. While [TCZ] demonstrates significant efficacy, it's crucial to remain vigilant about potential side effects and ensure ongoing monitoring to maintain patient safety and well-being.

Date :
  1. Date Completed 2023-02-08
  2. Date Revised 2023-03-24
Further Info :

Pubmed ID

35114930

DOI: Digital Object Identifier

10.2174/2772432817666220202115623

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.