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Extended-release methylphenidate for attention deficit hyperactivity disorder (ADHD) in adults.

Author: BoesenKim, GøtzschePeter C, JørgensenKarsten Juhl, Paludan-MüllerAsger Sand

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Extended-release methylphenidate compared to placebo improved ADHD symptoms in adults with ADHD, but the certainty of the evidence was very low due to high risk of bias and limitations in generalizability. The benefits and harms of extended-release methylphenidate remain uncertain.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is a psychiatric diagnosis increasingly used in adults. The recommended first-line pharmacological treatment is central nervous system (CNS) stimulants, such as methylphenidate, but uncertainty remains about its benefits and harms. OBJECTI...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869321/

データ提供：米国国立医学図書館（NLM）

Extended-Release Methylphenidate for ADHD in Adults: A Review of the Evidence

This systematic review delves into the [efficacy and safety of extended-release methylphenidate] for [attention deficit hyperactivity disorder (ADHD) in adults]. The authors reviewed a [comprehensive body of randomized controlled trials] to assess the [benefits and harms] of this medication. Their findings demonstrate [limited evidence for long-term effects] and highlight the [high risk of bias] in many of the included studies. The review underscores the [need for further research] to establish the [long-term efficacy and safety] of extended-release methylphenidate for ADHD in adults. A key takeaway from this research is the [importance of careful consideration of individual patient factors] and the [need for ongoing monitoring] when prescribing this medication.

Extended-Release Methylphenidate for ADHD in Adults: A Review of the Evidence

This review highlights the need for more rigorous research to fully understand the benefits and risks of extended-release methylphenidate for ADHD in adults. It emphasizes the importance of individualized treatment plans and ongoing monitoring to ensure optimal patient care.

Extended-Release Methylphenidate for ADHD in Adults: A Review of the Evidence

This research underscores the importance of a balanced approach to medication use for ADHD in adults. It highlights the need for careful consideration of individual patient needs, the potential benefits and risks of treatment, and the importance of ongoing research to improve our understanding of this complex condition.

Dr.Camel's Conclusion

The desert, with its endless expanse and unpredictable shifts, is a fitting representation of the challenges faced by individuals with ADHD. This research, like a camel traversing the dunes, seeks to navigate the complexities of this condition and assess the efficacy and safety of extended-release methylphenidate. The findings highlight the need for further exploration and emphasize the importance of individualized care in this complex medical landscape.

Date :
  1. Date Completed 2022-03-01
  2. Date Revised 2023-11-24
Further Info :

Pubmed ID

35201607

DOI: Digital Object Identifier

PMC8869321

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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