Paper Details

  1. Home
  2. Paper Details

Efficacy of propylthiouracil in the treatment of pregnancy with hyperthyroidism and its effect on pregnancy outcomes: A meta-analysis.

Author: LiuWenwen, MiaoYiqun, TengPing, WangAihua, XuYang, ZhangYuanyuan, ZhouYun

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.

Overview

This meta-analysis found that propylthiouracil (PTU) treatment for hyperthyroidism during pregnancy was not associated with an increased risk of congenital anomalies, neonatal hypothyroidism, or hepatotoxicity. The findings support the use of PTU during pregnancy with hyperthyroidism to improve clinical pregnancy outcomes in patients with thyroid dysfunction.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Hyperthyroidism affects about 0.2%-2.7% of all pregnancies, and is generally treated with propylthiouracil (PTU). However, previous studies about the effects of propylthiouracil on maternal or foetal are contentious. OBJECTIVE: This meta-analysis was carried out to investigate the safet...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912150/

データ提供：米国国立医学図書館（NLM）

Propylthiouracil: Navigating the Sands of Hyperthyroidism in Pregnancy

Hyperthyroidism during pregnancy is a complex condition that can pose challenges for both mother and child. This meta-analysis, like a comprehensive map guiding us through a vast and intricate desert, evaluates the safety and efficacy of propylthiouracil (PTU) in treating hyperthyroidism during pregnancy. The researchers meticulously analyzed existing studies to provide a clearer picture of the risks and benefits of this medication.

A Journey Through the Labyrinth of Pregnancy

The meta-analysis, incorporating data from 13 studies involving over 18,000 infants, concluded that PTU is generally safe and effective for treating hyperthyroidism during pregnancy. No significant association was found between PTU use and congenital anomalies, neonatal hypothyroidism, or hepatotoxicity.

Guiding Mothers Through a Stormy Desert

This meta-analysis provides reassuring evidence for expectant mothers facing hyperthyroidism. PTU, a medication that can help manage this condition, appears to be safe for both mother and baby. However, it is essential to consult with a healthcare professional for personalized advice and treatment options.

Dr. Camel's Conclusion

This meta-analysis offers a valuable resource for understanding the role of PTU in managing hyperthyroidism during pregnancy. The findings provide comfort and guidance for expectant mothers, demonstrating that PTU can be a safe and effective treatment option for this challenging condition.

Date :
  1. Date Completed 2022-05-03
  2. Date Revised 2022-05-03
Further Info :

Pubmed ID

35271661

DOI: Digital Object Identifier

PMC8912150

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.