Paper Details 
Original Abstract of the Article :
IMPORTANCE: Clinical data on the use of overactive bladder (OAB) medications are limited by the physician interpretation of adverse effects rather than those that are patient reported. OBJECTIVE: The aim of the study was to evaluate the association between OAB medications and adverse drug events (A...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/35536677

データ提供:米国国立医学図書館(NLM)

Decoding the Side Effects of Overactive Bladder Medications

Overactive bladder (OAB) is a common condition that affects millions of people. This study delves into the adverse events associated with OAB medications using the U.S. Food and Drug Administration Adverse Event Reporting System (FAERS) database. This database is a rich source of information about adverse effects reported by patients, providing a valuable resource for understanding the potential risks of various medications.

Unraveling the Side Effects: Neuropsychiatric Concerns and More

The study found that the most frequently reported OAB medications were mirabegron, transdermal oxybutynin, and solifenacin. Neuropsychiatric (NP) adverse events were most commonly reported with tolterodine and fesoterodine, while transdermal oxybutynin had the lowest reported NP adverse events. Interestingly, increasing the dose of tolterodine or fesoterodine did not correlate with an increase in NP adverse events. Oxybutynin was associated with the highest risk of mood disorders, agitation, and balance problems, but the lowest risk of headaches. Mirabegron had a lower risk of mood disorders and agitation but a higher risk of headaches and migraines. These findings highlight the importance of carefully considering the potential side effects of different OAB medications and discussing them with your healthcare provider.

A Look at Medication Options and Patient Safety

The FAERS database reveals valuable insights into the potential risks associated with OAB medications. This information is crucial for making informed decisions about treatment options. If you are considering OAB medications, it's important to discuss your concerns with your healthcare provider and weigh the potential benefits against the risks. Together, you can develop a personalized treatment plan that addresses your needs and minimizes potential side effects.

Dr.Camel's Conclusion

Like a careful traveler navigating a desert, it's crucial to understand the landscape of potential side effects when choosing OAB medications. This research offers valuable insights into the potential risks associated with different OAB medications, helping patients and their healthcare providers make informed decisions about treatment options. Remember, knowledge is power, and understanding these potential risks is essential for navigating the path to better bladder health.

Date :
  1. Date Completed 2022-06-30
  2. Date Revised 2022-10-26
Further Info :

Pubmed ID

35536677

DOI: Digital Object Identifier

01436319-990000000-00015

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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