Brain-derived neurotrophic factor (BDNF) levels in children and adolescents before and after stimulant use a systematic review and metanalysis.

Author: CardosoSílvia Almeida, HenriquesBruno David, MoreiraTiago Ricardo, PimentelMaria Eduarda Oliveira, RaimundoCleuberton Kenedy Oliveira, de LuccaMarina Silva, de MirandaDébora Marques

Paper Details 
Original Abstract of the Article :
Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder associated with cognitive, social, and academic impairment. Neurotrophins, particularly brain-derived neurotrophic factor (BDNF), have been implicated in the pathophysiology of ADHD and response to stimulant treatment. ...See full text at original site
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引用元:
https://doi.org/10.1016/j.pnpbp.2023.110761

データ提供:米国国立医学図書館(NLM)

The Role of BDNF in ADHD: A Journey Through Neurodevelopment

In the field of [neurodevelopmental disorders], [attention deficit hyperactivity disorder (ADHD)] is a complex condition with a significant impact on children and adolescents. This research explores the potential role of [brain-derived neurotrophic factor (BDNF)], a protein involved in [brain development and function], in the [pathophysiology and treatment] of ADHD. The authors conducted a [systematic review and meta-analysis] of studies investigating [BDNF levels] in children and adolescents with ADHD, both before and after [treatment with stimulants]. Their findings suggest that [BDNF levels] might be [associated with ADHD] and potentially [influenced by stimulant treatment], although the specific mechanisms and clinical implications require further investigation. This research is like a desert explorer meticulously mapping a complex network of interconnected pathways, revealing clues to a better understanding of ADHD.

Unveiling the Secrets of BDNF in ADHD

This research provides valuable insights into the potential role of BDNF in the [development and treatment] of ADHD. While the findings suggest a possible link between BDNF and stimulant response, further research is needed to confirm this association and explore its clinical implications. Just as a camel navigates the desert with a keen sense of direction, we must continue to explore the intricate pathways of neurodevelopment to find effective treatments for conditions like ADHD.

Navigating the Desert of Neurodevelopmental Disorders

ADHD can pose significant challenges for individuals and families. This research highlights the importance of [ongoing research and personalized treatment plans] for children and adolescents with ADHD. We must continue to explore [innovative therapies] and [evidence-based approaches] to help these individuals reach their full potential. Just as a camel adapts to the harsh desert environment, we must adapt our understanding of neurodevelopmental disorders to provide the most effective care possible.

Dr.Camel's Conclusion

This research provides a valuable contribution to our understanding of the complex interplay between BDNF and ADHD. As we continue to unravel the secrets of neurodevelopment, we must embrace a spirit of discovery and innovation to find effective treatments for this challenging condition. As a wise camel, I encourage everyone to stay informed about the latest advancements in medical research and to seek the guidance of qualified professionals for personalized treatment strategies.
Date :
  1. Date Completed 2023-10-20
  2. Date Revised 2023-10-20
Further Info :

Pubmed ID

37044279

DOI: Digital Object Identifier

10.1016/j.pnpbp.2023.110761

SNS
PICO Info
in preparation
Languages

English

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