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Rapid tranquilization: a comparison of thiothixene with loxapine.

Author: DubinW R, WeissK J

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Loxapine and thiothixene were both effective for rapid tranquilization of acutely disturbed, psychotic patients. Loxapine had a significantly faster time to tranquilization than thiothixene. Side effects were minimal during the intramuscular phase, while dystonia was the most common side effect during the oral phase.
Paper Details　
Original Abstract of the Article :
This 6-day study evaluated the efficacy of equivalent doses of loxapine and thiothixene for rapid tranquilization of acutely disturbed, psychotic patients. After initial tranquilization with intramuscular injections for 24 hours, 58 patients were treated for 5 days with oral medication. With both dr...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/3711026

データ提供：米国国立医学図書館（NLM）

Rapid Tranquilization: A Race Against Time

In the world of mental health, time is often of the essence. Imagine a turbulent desert storm, a whirlwind of emotions and anxieties. This study investigates the use of loxapine and thiothixene to swiftly calm acutely disturbed, psychotic patients. The researchers delve into the intricacies of rapid tranquilization, comparing the efficacy and side effects of these two medications. This research sheds light on the delicate dance between therapeutic effectiveness and patient safety.

Finding Calm in the Storm: A Comparative Study

The study found that both loxapine and thiothixene were effective in reducing symptoms, but loxapine achieved quicker results. Think of this as navigating the storm with a skilled navigator, using the right tool for the job. The researchers carefully chart the course of treatment, highlighting the differences in onset of action and side effect profiles between the two medications.

Navigating the Mental Health Desert: A Guide to Treatment Options

This study provides valuable insights for clinicians treating acute psychotic states. The desert of mental health is a complex and challenging landscape, filled with emotional storms and uncertainties. The authors offer a roadmap for navigating this terrain, providing information to guide the choice of medication and optimize patient care.

Dr. Camel's Conclusion

Rapid tranquilization is a crucial aspect of mental health care, especially in emergency situations. This research provides a valuable comparison of two medications, highlighting their effectiveness and potential side effects. The journey through the mental health desert is often fraught with challenges, and this study offers crucial knowledge to guide our path towards better treatment outcomes.

Date :
  1. Date Completed 1986-07-09
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

3711026

DOI: Digital Object Identifier

3711026

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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