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Potassium Magnesium Citrate Is Superior to Potassium Chloride in Reversing Metabolic Side Effects of Chlorthalidone.

Author: GiaconaJohn M, JohnsonTalon, KhanGhazi, MoeOrson W, MurilloAshley, PakCharles C Y, PittmanDanielle, RenJimin, VongpatanasinWanpen, WangJijia

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Thiazide diuretics (TD) are often prescribed to treat hypertension. However, they can also increase the risk of diabetes. This study aims to investigate the effect of potassium magnesium citrate (KMgCit) on fasting plasma glucose and liver fat during TD therapy.
Paper Details　
Original Abstract of the Article :
Thiazide diuretics (TD) are the first-line treatment of hypertension because of its consistent benefit in lowering blood pressure and cardiovascular risk. TD is also known to cause an excess risk of diabetes, which may limit long-term use. Although potassium (K) depletion was thought to be the main ...See full text at original site
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引用元：
https://doi.org/10.1161/HYPERTENSIONAHA.123.21932

データ提供：米国国立医学図書館（NLM）

Potassium Magnesium Citrate: A Superior Choice for Reversing Chlorthalidone's Metabolic Side Effects?

Thiazide diuretics (TDs), commonly used to lower blood pressure, can have metabolic side effects, including hyperglycemia, which can limit their long-term use. This research investigates the effects of potassium magnesium citrate (KMgCit) in reversing the metabolic side effects of chlorthalidone, a commonly prescribed TD.

Examining the Effects of KMgCit on Chlorthalidone's Metabolic Side Effects

The study examined the effects of KMgCit on fasting plasma glucose and liver fat in patients receiving chlorthalidone therapy. Researchers aimed to determine whether KMgCit could effectively mitigate the metabolic side effects associated with TD use, offering a potentially safer approach to managing hypertension.

KMgCit: A Potential for Improved Metabolic Outcomes

The study's findings suggest that KMgCit may be superior to potassium chloride in reversing the metabolic side effects of chlorthalidone. The researchers observed improvements in fasting plasma glucose and liver fat levels in patients receiving KMgCit, highlighting its potential as a valuable adjunct to TD therapy.

Dr.Camel's Conclusion

Finding a way to manage hypertension without sacrificing metabolic health is like discovering a hidden oasis in the desert of cardiovascular disease. This study suggests that KMgCit might offer a safer and more effective approach to managing the metabolic side effects of chlorthalidone, providing a more balanced approach to hypertension treatment.

Date :
  1. Date Completed 2023-11-28
  2. Date Revised 2023-11-28
Further Info :

Pubmed ID

37846572

DOI: Digital Object Identifier

10.1161/HYPERTENSIONAHA.123.21932

SNS
PICO Info
in preparation
Languages

English

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