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Therapeutic Approach for Trigeminal Neuralgia: A Systematic Review.

Author: BaigFawaz Abdul Hamid, DasGotam, HameedMohammad Shahul, IshfaqMuhammad, JavaliMukhatar Ahmed, KhaderMohasin Abdul, KhalidImran, KhanAbdul Ahad Ghaffar, KotaMohammad Zahir, RanaMuhammad Haseeb, ShaikSharaz

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Carbamazepine and oxcarbazepine are considered the first-line drugs for treating classical trigeminal neuralgia (TN). Lamotrigine and baclofen can be used as second-line options if the first-line drugs are ineffective or cause intolerable side effects. While anticonvulsants are effective in managing TN, more research is needed on other drugs, combination therapies, and newer formulations.
Paper Details　
Original Abstract of the Article :
This umbrella review aimed to determine the various drugs used to treat trigeminal neuralgia (TN) and to evaluate their efficacies as well as side effects by surveying previously published reviews. An online search was conducted using PubMed, CRD, EBSCO, Web of Science, Scopus, and the Cochrane Libr...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10604820/

データ提供：米国国立医学図書館（NLM）

Navigating the Desert of Trigeminal Neuralgia: A Review of Therapeutic Approaches

Trigeminal neuralgia (TN) is a debilitating condition, like a desert mirage that creates illusions of pain. This umbrella review examines the various drug therapies used to treat TN, exploring their effectiveness and potential side effects. It's like mapping out the different paths through a pain-filled desert, seeking the most effective route to relief. The authors surveyed previously published reviews of randomized controlled trials.

Carbamazepine and Oxcarbazepine: Leading the Way in Trigeminal Neuralgia Treatment

The review confirms that carbamazepine and oxcarbazepine remain the first-line treatment options for classical TN. It's like finding two dependable oases in the desert, providing consistent relief from the pain. Other medications, like lamotrigine and baclofen, are considered second-line options for patients who don't respond well to carbamazepine.

Managing Trigeminal Neuralgia with a Multifaceted Approach

The review emphasizes the importance of a multidisciplinary approach, involving both medication and other therapies, such as botulinum toxin injections for refractory cases. It's like recognizing that different strategies might be needed to navigate different parts of the desert.

Dr.Camel's Conclusion

This review is a valuable resource for understanding the current landscape of TN treatment, offering a roadmap for finding the best path to pain relief. It's like having a compass in the desert, guiding us towards a brighter future free from the torment of TN.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-10-30
Further Info :

Pubmed ID

37892981

DOI: Digital Object Identifier

PMC10604820

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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